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胃食管反流病与阵发性心房颤动消融术

Gastro-Esophageal Reflux Disease and Paroxysmal Atrial Fibrillation Ablation.

作者信息

Floria Mariana, Iov Diana-Elena, Tanase Daniela Maria, Barboi Oana Bogdana, Baroi Genoveva Livia, Burlacu Alexandru, Grecu Mihaela, Sascau Radu Andy, Statescu Cristian, Mihai Catalina, Drug Vasile Liviu

机构信息

Department of Internal Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.

Internal Medicine Clinic, Saint Spiridon Emergency Hospital, 700115 Iași, Romania.

出版信息

Life (Basel). 2023 Apr 28;13(5):1107. doi: 10.3390/life13051107.

Abstract

UNLABELLED

Patients undergoing ablation for atrial fibrillation may be at increased risk of developing gastroesophageal reflux disease. We prospectively studied the presence of symptomatic gastroesophageal reflux disease in naïve patients who underwent atrial fibrillation ablation.

METHODS

The presence of typical symptoms suggestive of gastroesophageal reflux disease was clinically assessed by the gastroenterologist at baseline and at 3 months after ablation. In addition to that, all patients underwent upper gastrointestinal endoscopy.

RESULTS

Seventy-five patients were included in two groups: 46 patients who underwent atrial fibrillation ablation (study group) and 29 patients without ablation (control group). Patients with atrial fibrillation ablation were younger (57.76 ± 7.66 years versus 67.81 ± 8.52 years; = 0.001), predominantly male (62.2% versus 33.3%; = 0.030) and with higher body mass index (28.96 ± 3.12 kg/m versus 26.81 ± 5.19 kg/m; = 0.046). At three months after the ablation, in the study and control groups, there were 88.9% and 57.1% patients in sinus rhythm, respectively, ( = 0.009). Symptomatic gastroesophageal reflux disease was not more frequent in the study group (42.2% versus 61.9%; = 0.220). There was no difference in terms of sinus rhythm prevalence in patients with versus without symptomatic gastroesophageal reflux disease (89.5% versus 88.5%; = 0.709).

CONCLUSION

In this small prospective study, typical symptoms suggestive of gastroesophageal reflux disease were not more frequent three months following atrial fibrillation ablation.

摘要

未标注

接受房颤消融术的患者发生胃食管反流病的风险可能会增加。我们对接受房颤消融术的初治患者中症状性胃食管反流病的存在情况进行了前瞻性研究。

方法

由胃肠病学家在基线和消融术后3个月对提示胃食管反流病的典型症状进行临床评估。除此之外,所有患者均接受了上消化道内镜检查。

结果

75例患者被纳入两组:46例接受房颤消融术的患者(研究组)和29例未接受消融术的患者(对照组)。接受房颤消融术的患者更年轻(57.76±7.66岁对67.81±8.52岁;P=0.001),男性居多(62.2%对33.3%;P=0.030),且体重指数更高(28.96±3.12kg/m对26.81±5.19kg/m;P=0.046)。消融术后3个月,研究组和对照组分别有88.9%和57.1%的患者处于窦性心律(P=0.009)。研究组中症状性胃食管反流病并不更常见(42.2%对61.9%;P=0.220)。有症状性胃食管反流病的患者与无症状性胃食管反流病的患者在窦性心律患病率方面无差异(89.5%对88.5%;P=0.709)。

结论

在这项小型前瞻性研究中,提示胃食管反流病的典型症状在房颤消融术后3个月并不更常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6959/10220808/c117c33693a4/life-13-01107-g001.jpg

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