纳豆NB205及其突变体NBMK308对老龄蛋鸡鸡蛋品质的影响。

Effects of Natto NB205 and Its Mutant NBMK308 on Egg Quality in Aging Laying Hens.

作者信息

Liao Chaoyong, Cui Jian, Lei Jiaqi, Guo Yuming, Zhang Bingkun

机构信息

State Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

出版信息

Life (Basel). 2023 Apr 29;13(5):1109. doi: 10.3390/life13051109.

In aging laying hens, reproductive changes reduce egg quality. natto () is a versatile bacterium with high vitamin K2 content, providing health benefits for animals and humans. This study investigated the effect of natto NB205 and its mutant NBMK308 on egg quality in aging laying hens. Results showed that NB205 and NBMK308 supplementation significantly improved albumen height ( < 0.001), Haugh units ( < 0.05), and eggshell thickness ( < 0.001) compared to the control group. Supplementation also increased ovalbumin expression, regulated tight junction (TJ) proteins, reduced pro-inflammatory cytokine levels, and improved the health and productivity of aging laying hens by regulating key apoptosis-related genes in the magnum part of the oviduct. There were differences in the expression of vitamin K-dependent proteins (VKDPs) in the magnum between NB205 and NBMK308, but no significant differences in the improvement of egg quality. Supplementation with NB205 and NBMK308 can improve egg quality in aging laying hens.

在老龄蛋鸡中，生殖变化会降低蛋的品质。纳豆杆菌（）是一种富含高维生素K2的多功能细菌，对动物和人类都有益健康。本研究调查了纳豆杆菌NB205及其突变体NBMK308对老龄蛋鸡蛋品质的影响。结果表明，与对照组相比，添加NB205和NBMK308显著提高了蛋白高度（<0.001）、哈氏单位（<0.05）和蛋壳厚度（<0.001）。添加还增加了卵清蛋白表达，调节紧密连接（TJ）蛋白，降低促炎细胞因子水平，并通过调节输卵管峡部关键凋亡相关基因改善老龄蛋鸡的健康和生产性能。NB205和NBMK308之间输卵管峡部维生素K依赖蛋白（VKDPs）的表达存在差异，但在改善蛋品质方面无显著差异。添加NB205和NBMK308可改善老龄蛋鸡的蛋品质。