Harvey K J, Stewart R, Hemming M, Naismith N, Moulds R F
Med J Aust. 1986 Jul 7;145(1):28-32. doi: 10.5694/j.1326-5377.1986.tb113736.x.
Antibiotic audits that were conducted within our hospital between 1978 and 1982 showed persisting patterns of inappropriate antibiotic use. A commercial advertising agency was commissioned to plan a campaign to change entrenched prescribing habits. Amoxycillin was chosen as the test drug because previous audits consistently had shown that its intravenous administration was prescribed more frequently than was that of benzylpenicillin in the treatment of primary pneumonia. In addition, amoxycillin given by mouth was prescribed six-hourly rather than eight-hourly in one-third of the patients who were surveyed. A three-month remedial campaign used direct mail (pads and pens), display stands and posters, all of which focused on the booklet Antibiotic guidelines. Educational material was placed wherever staff members congregated. At the end of the campaign, intravenously administered amoxycillin was used in only 8% of 50 patients with primary pneumonia and amoxycillin given by mouth was prescribed six-hourly in only 10% of 99 patients. These changed habits were sustained six months after the campaign but showed some fall-off 18 months after the campaign. The campaign costs of $10,000 were recouped within 12 months by savings on drug costs. It is concluded that educational advertising is an effective means of changing prescribing behaviour in a hospital.
1978年至1982年期间在我们医院进行的抗生素使用情况审查显示,存在持续不当使用抗生素的模式。我们委托一家商业广告公司策划一场活动,以改变根深蒂固的处方习惯。选择阿莫西林作为测试药物,因为之前的审查一直表明,在治疗原发性肺炎时,其静脉给药的处方频率高于苄青霉素。此外,在接受调查的三分之一患者中,口服阿莫西林的给药频率为每六小时一次,而非每八小时一次。一场为期三个月的纠正活动采用了直邮(便签本和笔)、展示架和海报,所有这些都围绕着《抗生素指南》手册展开。教育材料放置在工作人员聚集的任何地方。活动结束时,50例原发性肺炎患者中只有8%使用了静脉注射阿莫西林,99例患者中只有10%的口服阿莫西林处方频率为每六小时一次。这些改变后的习惯在活动结束后持续了六个月,但在活动结束18个月后有所下降。活动成本为10,000美元,通过节省药品成本在12个月内收回。结论是,教育广告是改变医院处方行为的有效手段。