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固定翼、吊索发射的无人机对全血血液功能的影响。

The impact of delivery by a fixed-wing, sling-launched unmanned aerial vehicle on the hematologic function of whole blood.

机构信息

From the United States Army Institute of Surgical Research (G.C.P., M.A.M.), JBSA-Fort Sam Houston, Texas.

出版信息

J Trauma Acute Care Surg. 2023 Aug 1;95(2S Suppl 1):S152-S156. doi: 10.1097/TA.0000000000004061. Epub 2023 May 29.

Abstract

BACKGROUND

Unmanned aerial vehicles (UAVs) have been shown to shorten delivery times of medical products in health care, providing a potential answer to the question of prehospital resuscitation where blood and blood products are not readily available. While the capabilities and efficiencies of delivery via UAVs are already well established, the postdelivery viability and hemostatic function of whole blood has not been examined.

METHODS

Whole blood units were sampled for a preflight control and loaded onto a fixed wing UAV. The UAVs flew in predetermined flight paths to either deliver via parachute drop or direct recovery after UAV capture by arresting gear. Postflight and preflight samples were assayed for coagulation function with thromboelastography, blood chemistry, and free hemoglobin to observe hemolysis.

RESULTS

No significant differences in any metric were observed between the blood samples assayed preflight versus those flown and parachute dropped or those flown and recovered from the UAV.

CONCLUSION

The use of UAVs for delivery of whole blood offers significant benefits for prehospital care. Further innovations in UAV and transportation technologies will expand on an already strong foundation.

LEVEL OF EVIDENCE

Therapeutic/Care Management; Level IV.

摘要

背景

无人机 (UAV) 已被证明可以缩短医疗保健产品的交付时间,为院前复苏提供了一种潜在的解决方案,即在血液和血液制品无法立即获得的情况下。虽然通过无人机进行交付的能力和效率已经得到充分证实,但尚未检查全血的交付后存活能力和止血功能。

方法

采集全血样本进行飞行前控制,并装载到固定翼无人机上。无人机按照预定的飞行路径飞行,通过降落伞空投或通过拦阻装置捕获后直接回收进行交付。对飞行后的样本和飞行前的样本进行血栓弹性描记术、血液化学和游离血红蛋白检测,以观察溶血情况。

结果

在飞行前与飞行并空投或飞行并从无人机上回收的样本之间,在任何指标上均未观察到显著差异。

结论

使用无人机输送全血为院前护理提供了显著的益处。在无人机和运输技术方面的进一步创新将在已经强大的基础上进一步扩展。

证据水平

治疗/护理管理;IV 级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e1/10389418/4ccd1ef06e48/jt-95-s152-g001.jpg

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