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Successful Rezafungin Treatment of an Azole-Resistant Chronic Mucocutaneous Candidiasis in a STAT-1 Gain-of-Function Patient.

作者信息

Melenotte Cléa, Ratiney Robert, Hermine Olivier, Bougnoux Marie-Elisabeth, Lanternier Fanny

机构信息

Service de Maladies Infectieuses et Tropicales, Faculté de Médecine, Hôpital Necker Enfants Malades, Assistance Publique des Hôpitaux de Paris, Université Paris-Cité, 149 Rue de Sèvres, 75015, Paris, France.

Service de Pharmacie, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants Malades, Paris, France.

出版信息

J Clin Immunol. 2023 Aug;43(6):1182-1184. doi: 10.1007/s10875-023-01519-2. Epub 2023 May 29.

DOI:10.1007/s10875-023-01519-2
PMID:37247108
Abstract
摘要

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Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial.瑞扎芬净与卡泊芬净治疗念珠菌血症和侵袭性念珠菌病的疗效比较(ReSTORE):一项多中心、双盲、双模拟、随机3期试验。
Lancet. 2023 Jan 7;401(10370):49-59. doi: 10.1016/S0140-6736(22)02324-8. Epub 2022 Nov 25.
2
Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors.三例 STAT1 获得性功能异常伴慢性黏膜皮肤念珠菌病患者接受 JAK 抑制剂治疗。
J Clin Immunol. 2023 Jan;43(1):136-150. doi: 10.1007/s10875-022-01351-0. Epub 2022 Sep 2.
3
Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.
2787 株酵母分离株的棘白菌素药敏模式:检测 FKS 突变的阈值的重要性。
Antimicrob Agents Chemother. 2022 May 17;66(5):e0172521. doi: 10.1128/aac.01725-21. Epub 2022 Apr 12.
4
The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin.抗真菌药物管线上的药物:福沙那韦、依柏西普、奥洛福康唑、泊沙康唑和瑞他康唑。
Drugs. 2021 Oct;81(15):1703-1729. doi: 10.1007/s40265-021-01611-0. Epub 2021 Oct 9.
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Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial.雷泽凡辛与卡泊芬净治疗念珠菌血症和侵袭性念珠菌病的 2 期随机、双盲研究:STRIVE 试验。
Clin Infect Dis. 2021 Dec 6;73(11):e3647-e3655. doi: 10.1093/cid/ciaa1380.
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Antimicrob Agents Chemother. 2015 Dec;59(12):7465-70. doi: 10.1128/AAC.01973-15. Epub 2015 Sep 21.