Laboratoire de Bactériologie Hygiène, CHU Lille, Univ Lille Nord de France.
Laboratoire de Biologie, Centre Hospitalier, Boulogne sur Mer.
New Microbiol. 2023 May;46(2):223-225.
Corynebacterium pseudodiphtheriticum, a Gram-positive rod belonging the oropharynx microbiota, is usually described in pulmonary infections, especially in immunocompromised patients. This paper describes a rare case of native aortic infectious endocarditis (IE) and reviews the literature on similar cases. A 62-year-old man with rheumatic fever since childhood was hospitalized for surgical treatment of a febrile IE due to C. diphtheriticum with a large vegetation (15.8 X 8.3 mm). MALDI-TOF-MS from strain isolated in positive blood cultures identified C. pseudodiphtheriticum (2.34), and 16S rRNA sequencing from the valve sample confirmed the identification. The summary of 25 cases shows that the outcome of an IE due to C. pseudodiphtheriticum is bad. The review of the literature shows that this agent found in blood cultures in a cardiovascular context deserves to be explored meticulously because an unfavorable prognosis is frequent.
假白喉棒状杆菌，一种属于口咽部微生物群的革兰阳性杆菌，通常在肺部感染中描述，特别是在免疫功能低下的患者中。本文描述了一例罕见的原发性主动脉感染性心内膜炎（IE）病例，并回顾了类似病例的文献。一名 62 岁的男性自幼患有风湿热，因 C. 白喉棒状杆菌引起的发热性 IE 住院，该患者有一个大的赘生物（15.8 X 8.3 毫米）。阳性血培养中分离的菌株的 MALDI-TOF-MS 鉴定为假白喉棒状杆菌（2.34），瓣膜样本的 16S rRNA 测序证实了鉴定结果。25 例病例总结表明，假白喉棒状杆菌引起的 IE 预后不良。文献回顾表明，在心血管环境中从血液培养中发现的这种病原体值得仔细探索，因为预后不良的情况很常见。
