评估哈萨克斯坦结直肠癌患者的生活质量。
Assessment of Quality of Life in Patients with Colorectal Cancer in Kazakhstan.
机构信息
Department of Epidemiology and Biostatistics, Semey Medical University, Semey, Republic of Kazakhstan.
Family Medicine, Department of Semey Medical University, Semey, Republic of Kazakhstan.
出版信息
Asian Pac J Cancer Prev. 2023 May 1;24(5):1827-1833. doi: 10.31557/APJCP.2023.24.5.1827.
BACKGROUND
The problem of quality of life (QOL) of patients with colorectal cancer (CRC) is particularly relevant due to the dynamics of CRC incidence growth. This study aims to assess QOL of patients with CRC in the Republic of Kazakhstan in order to give an idea about the impact of burden on QOL of patients.
METHODS
A total of 319 patients diagnosed with CRC participated in this one-stage cross-sectional study. The survey was conducted between November 2021 and June 2022 at cancer centers in Kazakhstan. Data were collected using the valid and reliable European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30, version 3.0).
RESULTS
The average age of respondents was 59, 23 (SD=10,604) years. The main age group 50-69 years old accounted for 62.1% of the total sample. Among all ill respondents, 153 (48%) were male and 166 (52%) were female. The mean global health status was 59.24 ± 22.62. Two of the five functional scales were below the ≥66.7% threshold, namely, emotional functioning 61.65 (28.04) and social functioning 61.96 (31.84); while scores for the other three were: physical functioning 69.38 (22.06), role functioning 69.69 (26.45), and cognitive functioning 74.60 (25.07).
CONCLUSIONS
This study gives an indication of good life functioning among our participants on the functional and symptom scales. However, they reported inadequate global health status.
背景
由于结直肠癌（CRC）发病率增长的动态变化，CRC 患者的生活质量（QOL）问题尤为重要。本研究旨在评估哈萨克斯坦共和国 CRC 患者的 QOL，以了解负担对患者 QOL 的影响。
方法
共有 319 名被诊断患有 CRC 的患者参加了这项单阶段横断面研究。调查于 2021 年 11 月至 2022 年 6 月在哈萨克斯坦的癌症中心进行。数据是使用有效的和可靠的欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30，版本 3.0）收集的。
结果
受访者的平均年龄为 59.23（标准差=10.604）岁。主要年龄组为 50-69 岁，占总样本的 62.1%。在所有患病的受访者中，153 人（48%）为男性，166 人（52%）为女性。全球健康状况的平均得分为 59.24±22.62。五个功能量表中有两个低于≥66.7%的阈值，分别是情感功能 61.65（28.04）和社会功能 61.96（31.84）；而其他三个量表的得分为：身体功能 69.38（22.06）、角色功能 69.69（26.45）和认知功能 74.60（25.07）。
结论
本研究表明，在我们的参与者中，功能和症状量表上的生活功能良好。然而，他们报告全球健康状况不佳。
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