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[颅内肿瘤中的肿瘤出血]

[Tumor hemorrhage in intracranial tumors].

作者信息

Albert F K

出版信息

Neurochirurgia (Stuttg). 1986 May;29(3):67-74. doi: 10.1055/s-2008-1053705.

Abstract

From 1975 to 1981, 50 patients with spontaneous hematomas due to intracranial tumours were treated in the Neurochirurgische Universitätsklinik Erlangen-Nürnberg. 33 tumours were located within the cerebral hemispheres, 6 within the oral brain stem, 6 tumours had a cerebellar origin, 2 neoplasms were located within the cerebellopontine angle, and 3 tumours grew in the sellar region. In most of the patients we found metastatic neoplasms (26%) and glioblastomas (22%), 6 tumours (12%) could not be identified histologically; 2 of these cases were assumed to be malignant gliomas. Two congenital tumours and a chondroma of the cerebellopontine angle were particularly notable. The incidence of tumour hemorrhage reported here was 4.1%. In 40 patients (80%) the hemorrhage was the cause of an acute clinical course, leading to death in 10 cases. 30% of the patients had to be operated on immediately, 32% were primarily treated in the intensive-care unit. Ten patients of the latter group died because of the acute hemorrhage. In the remaining 19 patients the course appeared to be less threatening and generally of an apoplectiform type. In about 50% the hemorrhage represented the first reliable sign of the hitherto asymptomatic tumour growth, in 32% it remained the only clinical diagnosis for a certain time. In 3 patients the brain tumours were not definitely diagnosed until some months later. One tumour was identified at autopsy. In pathological anatomy we could differentiate between several types of tumour bleedings. CT scan enabled the identification of the neoplastic origin in 86%, in 5 cases (10%) CT failed to yield the correct diagnosis. Twice CT scan had not been performed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1975年至1981年期间,埃尔朗根 - 纽伦堡大学神经外科诊所对50例因颅内肿瘤导致自发性血肿的患者进行了治疗。33个肿瘤位于大脑半球内,6个位于延髓,6个肿瘤起源于小脑,2个肿瘤位于桥小脑角,3个肿瘤生长在鞍区。在大多数患者中,我们发现了转移性肿瘤(26%)和胶质母细胞瘤(22%),6个肿瘤(12%)在组织学上无法确诊;其中2例被认为是恶性胶质瘤。两个先天性肿瘤和一个桥小脑角软骨瘤尤为引人注目。此处报道的肿瘤出血发生率为4.1%。在40例患者(80%)中,出血是急性临床病程的原因,导致10例死亡。30%的患者必须立即接受手术,32%主要在重症监护病房接受治疗。后一组中的10例患者因急性出血死亡。在其余19例患者中,病程似乎威胁较小,通常呈中风样类型。在约50%的患者中,出血是迄今无症状肿瘤生长的首个可靠迹象,在32%的患者中,在一段时间内它仍然是唯一的临床诊断。在3例患者中,直到数月后才明确诊断出脑肿瘤。1例肿瘤在尸检时被发现。在病理解剖中,我们可以区分几种类型的肿瘤出血。CT扫描能够在86%的病例中确定肿瘤起源,5例(10%)CT未能得出正确诊断。有两次未进行CT扫描。(摘要截取自250字)

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