Gupta Ankit, Mirpuri Lavesh, Malik Faizan, Hassan Hussain, Amtul Nasira
School of Medicine, University of Leeds, Worsley Building, Woodhouse, Leeds LS2 9JT, UK.
Leeds Institute of Emergency General Surgery, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
J Surg Case Rep. 2023 May 25;2023(5):rjad281. doi: 10.1093/jscr/rjad281. eCollection 2023 May.
Appendiceal collision tumours are extremely rare, with most reported cases describing tumours consisting of a mucinous component and a neuroendocrine component. Low-grade appendiceal mucinous neoplasms, in some cases, have a tendency to rupture and disseminate their mucin-producing cells throughout the abdominal cavity, leading to a clinical syndrome known as pseudomyxoma peritonei (PMP). We present the case of a 64-year-old male who initially presented with acute appendicitis and was subsequently found to have PMP and appendiceal malignancy. After several years of scans, surgical intervention and histological analysis, it became apparent that the appendiceal malignancy was comprised of distinct cell types. The patient underwent two rounds of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy, which resulted in a 2-year disease-free period. Unfortunately, the PMP recurred, having morphological changes consistent with a more aggressive disease process.
阑尾碰撞瘤极为罕见，大多数报道病例描述的肿瘤由黏液成分和神经内分泌成分组成。在某些情况下，低级别阑尾黏液性肿瘤有破裂并将其产生黏液的细胞播散至整个腹腔的倾向，导致一种称为腹膜假黏液瘤（PMP）的临床综合征。我们报告一例64岁男性病例，该患者最初表现为急性阑尾炎，随后被发现患有PMP和阑尾恶性肿瘤。经过数年的扫描、手术干预和组织学分析，发现阑尾恶性肿瘤由不同的细胞类型组成。该患者接受了两轮细胞减灭术及术中腹腔内热灌注化疗，获得了2年的无病生存期。不幸的是，PMP复发，其形态学改变与更具侵袭性的疾病进程相符。
