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Cardiovascular toxicities associated with loperamide use.
Eur Heart J Case Rep. 2023 Apr 18;7(5):ytad205. doi: 10.1093/ehjcr/ytad205. eCollection 2023 May.
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Cardiovascular Toxicities Associated With Loperamide: Analysis of the World Health Organization Pharmacovigilance Database.
Circulation. 2021 Jan 26;143(4):403-405. doi: 10.1161/CIRCULATIONAHA.120.050587. Epub 2021 Jan 25.
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Loperamide toxicity: recommendations for patient monitoring and management.
Clin Toxicol (Phila). 2020 May;58(5):355-359. doi: 10.1080/15563650.2019.1681443. Epub 2019 Nov 4.
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Loperamide misuse and abuse.
J Am Pharm Assoc (2003). 2017 Mar-Apr;57(2S):S45-S50. doi: 10.1016/j.japh.2016.12.079. Epub 2017 Feb 8.
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Ventricular fibrillation due to overdose of loperamide, the "poor man's methadone".
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Prospective, controlled, multicentre study of loperamide in pregnancy.
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Loperamide misuse to avoid opioid withdrawal and to achieve a euphoric effect: high doses and high risk.
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Loperamide: A Readily Available but Dangerous Opioid Substitute.
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引用本文的文献

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Reply to the letter to the editor.
Eur Heart J Case Rep. 2023 May 16;7(5):ytad241. doi: 10.1093/ehjcr/ytad241. eCollection 2023 May.

本文引用的文献

1
Loperamide-induced cardiogenic syncope: a case report of a life-threatening presentation of an over-the-counter drug.
Eur Heart J Case Rep. 2023 Feb 6;7(2):ytad059. doi: 10.1093/ehjcr/ytad059. eCollection 2023 Feb.
2
Cardiovascular Toxicities Associated With Loperamide: Analysis of the World Health Organization Pharmacovigilance Database.
Circulation. 2021 Jan 26;143(4):403-405. doi: 10.1161/CIRCULATIONAHA.120.050587. Epub 2021 Jan 25.
3
Potent Inhibition of hERG Channels by the Over-the-Counter Antidiarrheal Agent Loperamide.
JACC Clin Electrophysiol. 2016 Dec;2(7):784-789. doi: 10.1016/j.jacep.2016.07.008. Epub 2016 Sep 14.
4
Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic.
Naunyn Schmiedebergs Arch Pharmacol. 2016 Oct;389(10):1133-7. doi: 10.1007/s00210-016-1286-7. Epub 2016 Aug 16.

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