Cunningham M D, Ellison R C, Zierler S, Kanto W P, Miettinen O S, Nadas A S
Obstet Gynecol. 1986 Jul;68(1):41-5.
Data from 2107 inborn premature infants monitored for hemodynamically significant patent ductus arteriosus were used to develop means for clinically assessing at birth the risk of developing patent ductus arteriosus during the first 30 days of life. The overall 30-day incidence rates in birth weight categories 500 to 999, 1000 to 1499 g, and 1500 to 1750 g were 41, 17, and 7%, respectively. At-birth risk estimates obtainable from the derived multivariate functions ranged from 0 to 78% for the 500 to 999 and 1000- to 1499-g categories, and from 0 to 20% for the 1500- to 1750-g category. The derived risk functions provide for enhanced selectivity in the application of measures for the prevention of patent ductus arteriosus.
对2107例患有血流动力学显著意义的动脉导管未闭的早产新生儿的数据进行分析，以制定在出生时临床评估出生后30天内发生动脉导管未闭风险的方法。出生体重在500至999克、1000至1499克和1500至1750克的婴儿，其30天总体发病率分别为41%、17%和7%。通过推导的多变量函数得出的出生时风险估计值，在500至999克和1000至1499克体重类别中为0至78%，在1500至1750克体重类别中为0至20%。推导得出的风险函数提高了预防动脉导管未闭措施应用的选择性。
