Opoku Isaac, Atemnkeng Njika, Vila Nedsely
Internal Medicine, Piedmont Athens Regional, Athens, USA.
Cureus. 2023 Apr 26;15(4):e38171. doi: 10.7759/cureus.38171. eCollection 2023 Apr.
Milk-alkali syndrome is described by a triad of elevated levels of calcium, metabolic alkalosis, and acute kidney injury that historically occurred as a result of the combined intake of large amounts of calcium and absorbable alkali. It is becoming common recently with the use of over-the-counter calcium supplements for osteoporosis treatment in postmenopausal women. We present a case of a 62-year-old female who presented with generalized weakness. She was noted to have severe hypercalcemia, and impaired renal function with a significant history of daily over-the-counter calcium supplement use and as-needed calcium carbonate use for gastroesophageal reflux disease (GERD). This case highlights the stepwise approach to the evaluation and management of hypercalcemia. She was appropriately treated with the resolution of hypercalcemia and presenting symptoms.
乳碱综合征表现为钙水平升高、代谢性碱中毒和急性肾损伤三联征，既往是由于大量摄入钙和可吸收碱所致。近年来，随着非处方钙补充剂用于绝经后女性骨质疏松症的治疗，该综合征变得常见。我们报告一例62岁女性，表现为全身乏力。她被发现有严重高钙血症和肾功能损害，有大量每日服用非处方钙补充剂以及因胃食管反流病（GERD）按需使用碳酸钙的病史。该病例强调了高钙血症评估和管理的逐步方法。她经适当治疗后高钙血症及相关症状得到缓解。
