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胡芦巴的合成代谢作用:系统评价与荟萃分析。

The Anabolic Effect of Fenugreek: A Systematic Review with Meta-analysis.

机构信息

Institute for Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany.

Department of Fitness and Health, IST University of Applied Science, Dusseldorf, Dusseldorf, Germany.

出版信息

Int J Sports Med. 2023 Sep;44(10):692-703. doi: 10.1055/a-2048-5925. Epub 2023 May 30.

DOI:10.1055/a-2048-5925
PMID:37253363
Abstract

The use of plant steroids to improve physical health and performance is becoming increasingly popular. One of these plant steroids is diosgenin, which is mainly available in fenugreek. As a result, some studies have been conducted to improve physical health. Fenugreek extracts are also becoming increasingly popular in the context of athletic performance. Based on these assumptions, a systematic review with meta-analysis was conducted to evaluate the promoting effects of fenugreek on strength performance, body composition, and hormone concentration. Four databases were screened according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The current version of ReviewManager (RevMan) was used for the statistical evaluation. Seven studies with 449 participants (378 male, 71 female) met the inclusion criteria. A small effect of fenugreek was detected for total testosterone (standard mean difference (SMD): 0.32; 95% confidence interval (CI): 0.09 0.55), free testosterone (SMD: 0.24; 95% CI: -0.04, 0.52), lean body mass (SMD: 0.19; 95% CI: -0.10, 0.49), fat mass (SMD: -0.19; 95% CI: -0.44, 0.05), and leg press performance (SMD: 0.22; 95% CI: -0.02, 0.47), in male athletes. The meta-analysis shows that chronic application of fenugreek has performance-enhancing and anabolic effects in male athletes, but no statements can be made for female athletes.

摘要

植物甾体用于改善身体健康和表现的用途正变得越来越流行。其中一种植物甾体是薯蓣皂素,主要存在于胡芦巴中。因此,一些研究已经在进行,以改善身体健康。胡芦巴提取物在运动表现方面也越来越受欢迎。基于这些假设,进行了一项系统评价和荟萃分析,以评估胡芦巴对力量表现、身体成分和激素浓度的促进作用。根据系统评价和荟萃分析报告的首选项目 (PRISMA) 指南,筛选了四个数据库。当前版本的 ReviewManager (RevMan) 用于统计评估。有 7 项研究符合纳入标准,共纳入 449 名参与者(378 名男性,71 名女性)。胡芦巴对总睾酮(标准均数差 (SMD):0.32;95%置信区间 (CI):0.09 0.55)、游离睾酮(SMD:0.24;95% CI:-0.04,0.52)、瘦体重(SMD:0.19;95% CI:-0.10,0.49)、体脂量(SMD:-0.19;95% CI:-0.44,0.05)和腿推力量(SMD:0.22;95% CI:-0.02,0.47)有较小的影响。在男性运动员中,荟萃分析表明,胡芦巴的慢性应用具有增强表现和合成代谢作用,但不能对女性运动员做出任何陈述。

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