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韩国哮喘指南摘要。

Summary of Korean Asthma Guideline.

作者信息

Rhee Chin Kook, Moon Ji-Yong, Joo Hyonsoo, Jung Ji Ye, Lee Jung-Kyu, Min Kyung Hoon, Koo Hyeon-Kyoung, Lim Seong Yong, Yoon Hyoung Kyu, Lee Sang Yeub

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.

出版信息

Tuberc Respir Dis (Seoul). 2023 Jul;86(3):158-165. doi: 10.4046/trd.2023.0052. Epub 2023 May 30.

Abstract

Asthma is a chronic inflammatory airway disease that is characterized by variable airflow obstruction. The Korean Asthma Study Group of the Korean Academy of Tuberculosis and Respiratory Diseases has recently updated the Korean Asthma Guideline. This review summarizes the updated Korean Asthma Guideline. Asthma prevalence is increasing worldwide, and in Korea. Variable airflow obstruction can be confirmed by bronchodilator response or other tests, and should be established prior to the controller medication. A low-dose inhaled corticosteroid-formoterol is used to alleviate symptoms in all treatment step, and it can be used as a controller as well as reliever in steps 3-5. This approach is preferred, because it reduces the risk of severe exacerbations, compared to the use of short-acting β2-agonist as reliever. In severe asthma, phenotype/endotype based on the underlying inflammation should be evaluated. For type 2 severe asthma, the biologics should be considered.

摘要

哮喘是一种慢性炎症性气道疾病,其特征为气流阻塞多变。韩国结核病和呼吸疾病学会的韩国哮喘研究小组最近更新了韩国哮喘指南。本综述总结了更新后的韩国哮喘指南。全球范围内以及在韩国,哮喘患病率都在上升。气流阻塞多变可通过支气管扩张剂反应或其他检查来确认,且应在使用控制药物之前确定。低剂量吸入性糖皮质激素-福莫特罗用于所有治疗步骤中缓解症状,在3-5级步骤中它既可用作控制药物也可用作缓解药物。这种方法更可取,因为与使用短效β2受体激动剂作为缓解药物相比,它降低了严重加重发作的风险。在重度哮喘中,应评估基于潜在炎症的表型/内型。对于2型重度哮喘,应考虑使用生物制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c15/10323208/8567789353b5/trd-2023-0052f1.jpg

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