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1
Respiratory Reviews in Asthma 2022.《2022年哮喘呼吸综述》
Tuberc Respir Dis (Seoul). 2022 Oct;85(4):283-288. doi: 10.4046/trd.2022.0097. Epub 2022 Aug 16.
2
Exhaled nitric oxide is not elevated in the inflammatory airways diseases of cystic fibrosis and bronchiectasis.呼出一氧化氮在囊性纤维化和支气管扩张症等炎症性气道疾病中并未升高。
Eur Respir J. 1998 Dec;12(6):1290-4. doi: 10.1183/09031936.98.12061290.
3
Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study.重叠性哮喘和慢性鼻-鼻窦炎患者支气管扩张症的流行情况及其临床意义:一项单中心前瞻性研究。
BMC Pulm Med. 2021 Jul 5;21(1):211. doi: 10.1186/s12890-021-01575-7.
4
[Usefulness of measurement of nitric oxide in exhaled air in diagnostics and treatment of allergic rhinitis and asthma in children and adolescents].[呼出气中一氧化氮测量在儿童和青少年过敏性鼻炎及哮喘诊断与治疗中的应用价值]
Dev Period Med. 2018;22(2):135-143. doi: 10.34763/devperiodmed.20182202.135143.
5
Exhaled nitric oxide--is it really a good marker of airway inflammation in bronchial asthma?呼出一氧化氮——它真的是支气管哮喘气道炎症的良好标志物吗?
Respiration. 2000;67(6):645-51. doi: 10.1159/000056294.
6
Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.每日一次单吸入器三联疗法(FF/UMEC/VI)与FF/VI治疗哮喘控制不佳患者的疗效和安全性(CAPTAIN):一项双盲、随机、3A期试验
Lancet Respir Med. 2021 Jan;9(1):69-84. doi: 10.1016/S2213-2600(20)30389-1. Epub 2020 Sep 9.
7
Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults.基于呼出一氧化氮与临床症状的针对儿童和成人哮喘的个性化干预措施。
Cochrane Database Syst Rev. 2009 Oct 7(4):CD006340. doi: 10.1002/14651858.CD006340.pub3.
8
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Relationship between upper airway diseases, exhaled nitric oxide, and bronchial hyperresponsiveness to methacholine.上气道疾病、呼出一氧化氮与对乙酰甲胆碱的支气管高反应性之间的关系。
J Asthma. 2019 Jan;56(1):53-60. doi: 10.1080/02770903.2018.1429465. Epub 2018 Feb 12.
10
Cost utility of fractional exhaled nitric oxide monitoring for the management of children asthma.呼出一氧化氮分数监测在儿童哮喘管理中的成本效用
Cost Eff Resour Alloc. 2021 Jun 3;19(1):33. doi: 10.1186/s12962-021-00287-3.

引用本文的文献

1
Summary of Korean Asthma Guideline.韩国哮喘指南摘要。
Tuberc Respir Dis (Seoul). 2023 Jul;86(3):158-165. doi: 10.4046/trd.2023.0052. Epub 2023 May 30.

本文引用的文献

1
Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.应用呼出气一氧化氮测定指导哮喘治疗:美国胸科学会临床实践指南
Am J Respir Crit Care Med. 2021 Nov 15;204(10):e97-e109. doi: 10.1164/rccm.202109-2093ST.
2
Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma.伊特司珠单抗治疗中重度哮喘的疗效和安全性。
N Engl J Med. 2021 Oct 28;385(18):1656-1668. doi: 10.1056/NEJMoa2024257.
3
Asthma Phenotypes and COVID-19 Risk: A Population-based Observational Study.哮喘表型与 COVID-19 风险:基于人群的观察性研究。
Am J Respir Crit Care Med. 2022 Jan 1;205(1):36-45. doi: 10.1164/rccm.202107-1704OC.
4
Long-term safety and efficacy of dupilumab in patients with moderate-to-severe asthma (TRAVERSE): an open-label extension study.度普利尤单抗治疗中重度哮喘患者的长期安全性和有效性(TRAVERSE):一项开放标签扩展研究。
Lancet Respir Med. 2022 Jan;10(1):11-25. doi: 10.1016/S2213-2600(21)00322-2. Epub 2021 Sep 28.
5
Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study.重叠性哮喘和慢性鼻-鼻窦炎患者支气管扩张症的流行情况及其临床意义:一项单中心前瞻性研究。
BMC Pulm Med. 2021 Jul 5;21(1):211. doi: 10.1186/s12890-021-01575-7.
6
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations in patients with uncontrolled, moderate-to-severe asthma receiving placebo in the LIBERTY ASTHMA QUEST study: a post-hoc analysis.基线呼出气一氧化氮(FeNO)作为 LIBERTY ASTHMA QUEST 研究中接受安慰剂治疗的未控制的中重度哮喘患者随后发生严重哮喘加重的预后生物标志物:一项事后分析。
Lancet Respir Med. 2021 Oct;9(10):1165-1173. doi: 10.1016/S2213-2600(21)00124-7. Epub 2021 Jun 25.
7
Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis.三联吸入器疗法与中重度哮喘的哮喘结局:系统评价和荟萃分析。
JAMA. 2021 Jun 22;325(24):2466-2479. doi: 10.1001/jama.2021.7872.
8
Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.特泽布尔单抗在成人和青少年重症、未控制哮喘中的应用。
N Engl J Med. 2021 May 13;384(19):1800-1809. doi: 10.1056/NEJMoa2034975.
9
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.阿替戈利单抗(抗 ST2)治疗成人严重哮喘的疗效和安全性:一项随机临床试验。
J Allergy Clin Immunol. 2021 Sep;148(3):790-798. doi: 10.1016/j.jaci.2021.03.044. Epub 2021 Apr 16.
10
Hormone Replacement Therapy and Development of New Asthma.激素替代疗法与新哮喘的发展。
Chest. 2021 Jul;160(1):45-52. doi: 10.1016/j.chest.2021.01.054. Epub 2021 Mar 26.

《2022年哮喘呼吸综述》

Respiratory Reviews in Asthma 2022.

作者信息

Lee Ji Hye, Kim Jin-Young, Choi Jae Sung, Na Ju Ock

机构信息

Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Choenan, Republic of Korea.

出版信息

Tuberc Respir Dis (Seoul). 2022 Oct;85(4):283-288. doi: 10.4046/trd.2022.0097. Epub 2022 Aug 16.

DOI:10.4046/trd.2022.0097
PMID:35974425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9537659/
Abstract

Asthma is a chronic inflammatory disease of the airways characterized by varying and recurrent symptoms, reversible airway obstruction, and bronchospasm. In this paper, clinical important studies on asthma published between March 2021 and February 2022 were reviewed. A study on the relationship between asthma and chronic rhinosinusitis, bronchiectasis, and hormone replacement therapy was published. A journal on the usefulness of fractional exhaled nitric oxide for the prediction of severe acute exacerbation was also introduced. Studies on the effect of inhaler, one of the most important treatments for asthma, were published. Studies on the control of severe asthma continued. Phase 2 and 3 studies of new biologics were also published. As the coronavirus disease 2019 (COVID-19) pandemic has been prolonged, many studies have explored the prevalence and mortality of COVID-19 infection in asthma patients.

摘要

哮喘是一种气道慢性炎症性疾病,其特征为症状多变且反复发作、气道可逆性阻塞以及支气管痉挛。本文回顾了2021年3月至2022年2月间发表的有关哮喘的重要临床研究。一项关于哮喘与慢性鼻-鼻窦炎、支气管扩张和激素替代疗法之间关系的研究已发表。还介绍了一篇关于呼出气一氧化氮分数对预测严重急性加重的有用性的期刊文章。有关哮喘最重要治疗方法之一的吸入器效果的研究已发表。关于重度哮喘控制的研究仍在继续。新型生物制剂的2期和3期研究也已发表。由于2019冠状病毒病(COVID-19)大流行持续存在,许多研究探讨了哮喘患者中COVID-19感染的患病率和死亡率。