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斯里兰卡抑郁症的患病率及相关因素:系统评价和荟萃分析。

Prevalence and associated factors of depression in Sri Lanka: a systematic review and meta-analysis.

机构信息

Department of Community Medicine, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka.

Department of Psychiatry, University of Kelaniya, Ragama, Sri Lanka.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2024 Feb;59(2):353-373. doi: 10.1007/s00127-023-02495-z. Epub 2023 May 31.

Abstract

PURPOSE

Epidemiological data on depression are required to inform policies and service planning in mental health in Sri Lanka. This review aimed to synthesise data from existing studies to calculate the pooled prevalence of depression in Sri Lanka, assess its variability across subgroups, and identify associated factors within each subgroup.

METHODS

PubMed, Embase, PsycINFO, Science Direct, Google Scholar and local journals were searched to identify peer-reviewed studies reporting the prevalence of depression among non-clinical adult, young, older, and maternal populations in Sri Lanka. A meta-analysis was performed using a random-effects model to calculate pooled prevalence estimates. Subgroup, sensitivity and moderator analyses were performed. A qualitative synthesis of factors associated with depression was conducted.

RESULTS

A total of 33 studies representing a total of 52,778 participants were included. Overall, the pooled prevalence of depression was 19.4% [14.44-25.54%]. Among subpopulations, the highest prevalence was reported among young persons (39%); the rates in adults, older persons and maternal populations were 8.7%, 18.4% and 16.9%, respectively. Prevalence estimates were higher when based on screening instruments (21.2%) compared to diagnostic interviews (4.3%). A high degree of heterogeneity (I = 99.2) was observed. A qualitative synthesis of factors associated with depression, including individual attributes and behaviours, socio-economic circumstances and broader environmental factors, is reported for each age group.

CONCLUSION

Approximately one-fifth of the population was detected to have depression. Notable variations in prevalence were observed across age groups. The heterogeneity of studies limits the inferences drawn from this review.

摘要

目的

需要有抑郁症的流行病学数据,为斯里兰卡精神卫生政策和服务规划提供信息。本综述旨在综合现有研究数据,计算斯里兰卡抑郁症的总患病率,评估其在亚组间的变异性,并确定每个亚组内的相关因素。

方法

检索了 PubMed、Embase、PsycINFO、Science Direct、Google Scholar 和当地期刊,以确定报告斯里兰卡非临床成年、青年、老年和孕产妇人群中抑郁症患病率的同行评议研究。使用随机效应模型进行荟萃分析,计算汇总患病率估计值。进行了亚组、敏感性和调节因素分析。对与抑郁症相关的因素进行了定性综合。

结果

共有 33 项研究代表了 52778 名参与者,总体而言,抑郁症的总患病率为 19.4%(14.44%-25.54%)。在亚人群中,年轻人的患病率最高(39%);成年人、老年人和孕产妇人群的患病率分别为 8.7%、18.4%和 16.9%。基于筛查工具的患病率估计值(21.2%)高于基于诊断访谈的患病率估计值(4.3%)。观察到高度的异质性(I=99.2)。对与抑郁症相关的因素进行了定性综合,包括个体属性和行为、社会经济状况以及更广泛的环境因素,按年龄组报告。

结论

大约五分之一的人口被检测出患有抑郁症。在不同年龄组中观察到患病率的显著差异。研究的异质性限制了本综述的推论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09c/10230494/b5f9ff3c2658/127_2023_2495_Fig1_HTML.jpg

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