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肺球孢子菌病合并非结核分枝杆菌肺病 1 例并文献复习

Pulmonary Coccidioidomycosis Complicated by Nontuberculous Mycobacterial Pulmonary Diseases with a Literature Review.

机构信息

Department of Respiratory Medicine, Nagasaki University Hospital, Japan.

Department of Respiratory Medicine, Nagasaki Medical Center, Japan.

出版信息

Jpn J Infect Dis. 2023 Sep 22;76(5):314-318. doi: 10.7883/yoken.JJID.2023.073. Epub 2023 May 31.

Abstract

Following an endobronchial examination, a young mine supervisor was treated with antibiotics for a pulmonary nontuberculous mycobacterial infection for approximately one year. However, a review of the radiological findings revealed a different possibility. Accordingly, pulmonary resection was performed, and histopathological analysis revealed numerous yeast-like fungi. Since the patient had stayed in the southwestern United States for two months in 2009, eight years previously, coccidioidomycosis was strongly suspected. The diagnosis of coccidioidomycosis was subsequently confirmed by serology and polymerase chain reaction testing of the excised specimen. Here, we report an educational case that emphasizes the importance of meticulous medical history-taking and awareness of endemic mycoses in other countries in the context of globalization.

摘要

在支气管镜检查后,一位年轻的矿山主管因肺部非结核分枝杆菌感染接受了大约一年的抗生素治疗。然而,对放射学发现的回顾揭示了一个不同的可能性。因此,进行了肺切除术,组织病理学分析显示出许多酵母样真菌。由于该患者在 8 年前的 2009 年曾在美国西南部停留过两个月,因此强烈怀疑为球孢子菌病。随后通过对切除标本的血清学和聚合酶链反应检测,确诊了球孢子菌病。在这里,我们报告了一个教育案例,强调了在全球化背景下,细致的病史采集和对其他国家地方性真菌病的认识的重要性。

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