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球孢子菌病:中国的输入性和可能的本土病例:病例报告和综述,1958-2017。

Coccidioidomycosis: Imported and possible domestic cases in China: A case report and review, 1958-2017.

机构信息

Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.

Department of Dermatology, The Affiliated Hospital of Qingdao University, Qingdao, China.

出版信息

Mycoses. 2018 Jul;61(7):506-513. doi: 10.1111/myc.12750. Epub 2018 Feb 19.

Abstract

We report a case of imported pulmonary coccidioidomycosis caused by Coccidioides posadasii in a patient who was misdiagnosed as tuberculosis and mistreated with antituberculosis medications for 18 months. The symptoms were not relieved until antifungal treatment was started. An extensive review of the coccidioidomycosis cases occurring in China reveals 38 cases, 16 of which had no associated history of travel to any traditional endemic areas. We speculate that some factors may drive Coccidioides spp. transference to China, which then causes those domestic infections. Moreover, we indicate the first, to the best of our knowledge, possible endemic areas in China.

摘要

我们报告了一例由 Coccidioides posadasii 引起的输入性肺球孢子菌病病例,该患者曾被误诊为肺结核,并接受了 18 个月的抗结核药物治疗,但症状并未缓解,直到开始抗真菌治疗。对在中国发生的球孢子菌病病例进行广泛回顾,发现有 38 例,其中 16 例无任何前往任何传统流行地区的旅行相关病史。我们推测,某些因素可能导致球孢子菌属转移到中国,进而导致这些国内感染。此外,我们指出了据我们所知中国的第一个可能的流行地区。

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