Kristal M B, Thompson A C, Heller S B, Komisaruk B R
Physiol Behav. 1986;36(6):1017-20. doi: 10.1016/0031-9384(86)90473-7.
Ingestion of placenta has previously been shown to enhance opiate-mediated analgesia (measured as tail-flick latency) induced either by morphine injection or by footshock. The present study was designed to test whether placenta ingestion would enhance the partly opiate-mediated analgesia produced by vaginal/cervical stimulation. Nulliparous Sprague-Dawley rats were tested for analgesia, using tail-flick latency, during and after vaginal/cervical stimulation; the tests for vaginal/cervical stimulation-induced analgesia were administered both before and after the rats ate placenta or ground beef. Placenta ingestion, but not beef ingestion, significantly heightened vaginal/cervical stimulation-induced analgesia. A subsequent morphine injection provided evidence that, as in a previous report, placenta ingestion, but not beef ingestion, enhanced morphine-induced analgesia.
先前的研究表明，摄入胎盘可增强由吗啡注射或电击足底诱导的阿片介导的镇痛作用（以甩尾潜伏期衡量）。本研究旨在测试摄入胎盘是否会增强由阴道/宫颈刺激产生的部分阿片介导的镇痛作用。选用未生育的斯普拉格-道利大鼠，在阴道/宫颈刺激期间及之后，使用甩尾潜伏期测试其镇痛效果；在大鼠食用胎盘或绞碎牛肉之前和之后，均进行阴道/宫颈刺激诱导镇痛的测试。摄入胎盘而非牛肉，可显著增强阴道/宫颈刺激诱导的镇痛作用。随后的吗啡注射提供了证据，正如之前的一份报告所述，摄入胎盘而非牛肉可增强吗啡诱导的镇痛作用。
