Suzuki S, Isshiki N, Ogawa Y, Goto M, Hayashi O
Plast Reconstr Surg. 1986 Aug;78(2):221-7. doi: 10.1097/00006534-198608000-00013.
In an attempt to clarify the delay phenomenon, the regional blood flow was measured in 10 undelayed flaps and 65 delayed flaps in rats by the clearance method with the electrolytically generated hydrogen. The ultimate purpose of this study was to establish the minimal requirement of blood flow for flap survival. The dye distance and the survival length were also measured. Blood flow in the flap increased with the delay period. Elongation of the survival length and the dye distance corresponded well to the circulatory enhancement. The present findings support the theory that delay improves blood circulation. The distance from the base to the 0.04-ml flow point was found to be highly correlated with survival length in the delayed groups as well as in the undelayed group. Based on the results, the minimal requirement of circulation for flap survival was assumed to be approximately 0.04 ml/min per gram of tissue whether or not the flap was delayed.
为了阐明延迟现象，采用电解产生氢气的清除法，对10只未延迟皮瓣和65只延迟皮瓣的大鼠进行了局部血流测量。本研究的最终目的是确定皮瓣存活所需的最小血流量。还测量了染料扩散距离和存活长度。皮瓣中的血流量随延迟时间的增加而增加。存活长度和染料扩散距离的延长与循环增强密切相关。目前的研究结果支持延迟可改善血液循环的理论。发现在延迟组和未延迟组中，从皮瓣基部到0.04毫升血流点的距离与存活长度高度相关。根据这些结果，无论皮瓣是否延迟，皮瓣存活所需的最小循环量假定约为每克组织0.04毫升/分钟。
