Algwaiz Ghada, Salam Yezan, Bustami Rami, Ferwana Mazen, Jazieh Abdul Rahman
Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Glob J Qual Saf Healthc. 2020 Dec 23;4(1):3-10. doi: 10.36401/JQSH-20-23. eCollection 2021 Feb.
Due to the complex nature of cancer cases, it is imperative that the involved healthcare providers coordinate the patients care plan in union to reach the best possible outcome in the smoothest and fastest manner. This is what multidisciplinary tumor board (MTB) meetings strive to achieve. Conducting regular MTB meetings requires significant investment of time and finances. It is thus vital to assess the empirical benefits of such practice.
A meta-analysis was conducted to evaluate the literature regarding the impact of MTB meetings on patient 5-year survival. Relevant studies were identified by searching Ovid MEDLINE and Embase databases from January 1995 to July 2019. Studies were included if they assessed 5-year survival in cases discussed in MTB meetings and used a comparison group and/or a pretest and posttest design.
Five articles met the study's inclusion criteria. Quality of studies was affected by selection bias and the use of historic cohorts. The results showed significantly improved 5-year survival in the MTB group compared with the non-MTB groups (odds ratio for 5-year death rate of 0.59, CI 0.45-0.78, < 0.001).
This meta-analysis showed that cancer MTB meetings have a significant impact on patients' 5-year survival. This could be because of several reasons, such as less time to treatment initiation, better adherence to guidelines, higher numbers of investigational imaging, lesser surgical complications, and recurrence rates. Future prospective studies are needed to further delineate reasons for improvement of outcome to enhance the benefits of this approach.
由于癌症病例的复杂性,相关医疗服务提供者必须联合协调患者的护理计划,以便以最顺畅、最快速的方式实现最佳治疗效果。这正是多学科肿瘤委员会(MTB)会议所努力达成的目标。定期召开MTB会议需要投入大量时间和资金。因此,评估这种做法的实际益处至关重要。
进行一项荟萃分析,以评估有关MTB会议对患者5年生存率影响的文献。通过检索1995年1月至2019年7月的Ovid MEDLINE和Embase数据库来确定相关研究。如果研究评估了MTB会议讨论病例的5年生存率,并使用了对照组和/或前后测试设计,则纳入研究。
五篇文章符合该研究的纳入标准。研究质量受到选择偏倚和历史队列使用的影响。结果显示,与非MTB组相比,MTB组的5年生存率显著提高(5年死亡率的优势比为0.59,CI 0.45 - 0.78,<0.001)。
这项荟萃分析表明,癌症MTB会议对患者的5年生存率有显著影响。这可能有几个原因,例如开始治疗的时间更短、对指南的遵循性更好、更多的影像学检查、更少的手术并发症和复发率。未来需要进行前瞻性研究,以进一步阐明改善治疗效果的原因,从而增强这种方法的益处。