Nakano I, Funakoshi A, Shinozaki H, Miyazaki K, Ibayashi H, Tateishi K, Hamaoka T
Regul Pept. 1986 May;14(3):229-36. doi: 10.1016/0167-0115(86)90005-4.
Postprandial responses of plasma cholecystokinin (CCK) in patients with non-insulin dependent diabetes mellitus (NIDDM) were studied with a CCK specific radioimmunoassay. After the ingestion of a liquid test meal, plasma CCK levels increased from the basal level of 9.8 +/- 1.1 pg/ml to a peak of 19.4 +/- 1.8 pg/ml at 20 min in healthy subjects (n = 10). The ingestion of a test meal in patients with NIDDM (n = 10) resulted in a significantly greater increase of plasma CCK than in healthy subjects and a significant increase of plasma CCK from a basal level of 14.2 +/- 4.4 pg/ml to a peak of 47.4 +/- 12.4 pg/ml at 10 min.
采用胆囊收缩素（CCK）特异性放射免疫分析法，研究了非胰岛素依赖型糖尿病（NIDDM）患者餐后血浆CCK的反应。健康受试者（n = 10）摄入液体试验餐之后，血浆CCK水平从基础水平9.8±1.1 pg/ml升高，在20分钟时达到峰值19.4±1.8 pg/ml。NIDDM患者（n = 10）摄入试验餐导致血浆CCK的升高显著高于健康受试者，血浆CCK从基础水平14.2±4.4 pg/ml显著升高，在10分钟时达到峰值47.4±12.4 pg/ml。
