Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, 603203, Tamil Nadu, India.
Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, 603203, Tamil Nadu, India.
Carbohydr Res. 2023 Aug;530:108855. doi: 10.1016/j.carres.2023.108855. Epub 2023 May 25.
β-glucosidases hydrolyse glycosidic bonds to release non-reducing terminal glucosyl residues from glycosides and oligosaccharides via catalytic mechanisms. It is very well known that the β-glucosidase enzyme is used in biorefineries for cellulose degradation, where β-glucosidases is the rate-limiting enzyme for the final glucose production from cellobiose. The β-glucosidase enzyme is used as a catalyst in other industrial sectors, including pharmaceuticals, breweries, dairy, and food processing. With the aid of β-glucosidase enzymes, cyanogenic glycosides and plant glycosides are transformed into sugar moiety and aglycones. These aglycone compounds are employed as aromatic compounds in the food processing and brewing industries. They are also used as medications and dietary supplements based on their pharmacological qualities. Applications of aglycones and the microbiological sources of β-glucosidase in aglycone production have been discussed in this review.
β-葡萄糖苷酶通过催化机制将糖苷和寡糖中的糖苷键水解，从而从糖苷和寡糖中释放出非还原末端的葡萄糖基残基。众所周知，β-葡萄糖苷酶在生物炼制厂中用于纤维素降解，其中β-葡萄糖苷酶是从纤维二糖最终生产葡萄糖的限速酶。β-葡萄糖苷酶还可用作其他工业领域的催化剂，包括制药、啤酒厂、乳制品和食品加工。借助β-葡萄糖苷酶，氰基糖苷和植物糖苷转化为糖部分和糖苷配基。这些糖苷配基化合物在食品加工和酿造工业中用作芳香化合物。基于其药理学特性，它们还被用作药物和膳食补充剂。本综述讨论了糖苷配基的应用以及β-葡萄糖苷酶在糖苷配基生产中的微生物来源。
