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连续股内收肌管阻滞在膝关节置换治疗中用于疼痛管理的效果:一项荟萃分析。

The effects of continuous catheter adductor canal block for pain management in knee replacement therapy: a meta-analysis.

作者信息

Jabur Aiden, Nam Hyun Jae, Dixon Asher, Cox Tynan, Randall Hayden, Sun Jing

机构信息

School of Medicine and Dentistry, Griffith University, Gold Coast, Australia.

School of Medicine, University of Sydney, Sydney, Australia.

出版信息

Knee Surg Relat Res. 2023 Jun 1;35(1):16. doi: 10.1186/s43019-023-00188-0.

Abstract

PURPOSE

Adductor canal block has emerged as a favourable element of multimodal analgesia regimens for total knee arthroplasty, due to the exclusive sensory blockade it provides. However, it is controversial as to whether a single shot or continuous technique adductor canal block is superior. This meta-analysis examined the effect of both these techniques on pain management associated with total knee arthroplasty.

METHODS

All randomised controlled trials published on Cochrane Library, PubMed, and EMBASE, Scopus, and PsychINFO were systematically searched. The PEDro scale was used to assess the quality of studies. A total of 8 articles, 2 of which were split by subgroup analyses to create 10 studies, with 828 adults were selected for inclusion in the analysis. The mean difference and effect size with a 95% confidence interval (CI) were analysed for the pooled results.

RESULTS

Statistically significant pooled effects of analgesia technique in favour of catheter use were found in the reduction of pain scores and VAS scores, and total rescue analgesia dosage. No significant changes were observed in the hospital stay time. Subgroup analysis revealed that patients with BMI 30 or more reported higher pain scores than those with BMI below 30.

CONCLUSION

Based upon studies that are currently available, our meta-analysis appears to demonstrate that continuous administration of analgesia through an adductor canal catheter provides greater pain reduction in total knee arthroplasty than single shot analgesia. Despite these current findings, future studies with larger sample sizes and greater control of study parameters are required to confirm the current findings.

摘要

目的

由于内收肌管阻滞能提供独特的感觉阻滞,它已成为全膝关节置换多模式镇痛方案中的一个有利组成部分。然而,单次注射或连续技术的内收肌管阻滞哪种更优仍存在争议。本荟萃分析研究了这两种技术对全膝关节置换相关疼痛管理的影响。

方法

系统检索了Cochrane图书馆、PubMed、EMBASE、Scopus和PsychINFO上发表的所有随机对照试验。使用PEDro量表评估研究质量。共纳入8篇文章,其中2篇通过亚组分析进行拆分,形成10项研究,选取828名成年人纳入分析。对汇总结果分析了平均差和效应量以及95%置信区间(CI)。

结果

在疼痛评分、视觉模拟评分(VAS)和总补救镇痛剂量方面,发现镇痛技术在支持使用导管方面有统计学意义的汇总效应。住院时间未观察到显著变化。亚组分析显示,体重指数(BMI)为30或更高的患者报告的疼痛评分高于BMI低于30的患者。

结论

基于目前可得的研究,我们的荟萃分析似乎表明,在内收肌管置入导管持续给药镇痛在全膝关节置换中比单次注射镇痛能更大程度地减轻疼痛。尽管有这些当前的发现,但仍需要未来进行更大样本量和对研究参数有更好控制的研究来证实当前的发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/410d/10236883/a53ff29ac295/43019_2023_188_Fig1_HTML.jpg

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