Hao W T, Ji S F, Zheng C H, Cui T, Wang Y
Tianjin Eye Hospital, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China.
School of Computer Science and Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China.
Zhonghua Yan Ke Za Zhi. 2023 Jun 11;59(6):436-443. doi: 10.3760/cma.j.cn112142-20220707-00327.
The objective of this retrospective study was to employ machine learning techniques to examine age-related traits of ocular aberrations in a substantial population with myopia and myopic astigmatism. This was a cross-sectional study. Data from a population of myopic and myopic astigmatism patients who underwent wavefront aberration examinations at the Refractive Surgery Center of Tianjin Eye Hospital in Tianjin, China, were collected continuously from January 2013 to July 2017. The data from the right eye of each individual were collected for analysis. Each eye had 32 outcome data points, including age, best-corrected visual acuity (BCVA), lower-order aberrations (spherical diopter, cylindrical diopter, and astigmatic axis), and higher-order aberrations [Zernike coefficients and root mean square (RMS) of the third to sixth order aberrations] were analyzed. Higher-order aberrations were measured by Hartmann-Shack aberrometer. The study included 1 507 subjects (1 507 eyes), comprising of 694 males and 813 females, with a mean age of (23.28±5.45) years. The findings demonstrated a decrease followed by an increase in most of the higher-order aberrations with age between 15-40 years. The minimum value points were observed in the age group of 25-30 years for RMS of total higher-order aberrations, 3rd RMS (with a confidence of 47.74% for range 1), 4th RMS (with a confidence of 86.01% for range 1), and trefoil aberrations (with a confidence of 56.38% for C and 73.25% for C). The minimum value points were also observed in the age group of 30-35 years for primary spherical aberration (with a confidence of 56.10% for C) and vertical coma-like aberration (with a confidence of 56.91% for C). In contrast, astigmatism with the rule tended to decrease with age, while astigmatism against the rule and oblique astigmatism tended to increase (with a confidence of 88.66%, 84.71%, 81.07%, 79.67%, and 66.35% for astigmatism with the rule in different age groups). As age increases, the population with with-the-rule astigmatism decreases while the population with against-the-rule astigmatism increases. The high-order aberrations are the lowest in the 25-35 age group.
这项回顾性研究的目的是运用机器学习技术，在大量近视和近视散光人群中研究眼像差的年龄相关特征。这是一项横断面研究。连续收集了2013年1月至2017年7月在中国天津眼科医院屈光手术中心接受波前像差检查的近视和近视散光患者的数据。收集每个个体右眼的数据进行分析。每只眼睛有32个结果数据点，包括年龄、最佳矫正视力（BCVA）、低阶像差（球镜度数、柱镜度数和散光轴），并分析高阶像差[泽尼克系数以及三阶至六阶像差的均方根（RMS）]。高阶像差由哈特曼-夏克像差仪测量。该研究纳入了1507名受试者（1507只眼），其中男性694名，女性813名，平均年龄为（23.28±5.45）岁。研究结果表明，在15至40岁之间，大多数高阶像差随年龄先下降后上升。在25至30岁年龄组中观察到总高阶像差RMS、三阶RMS（范围1的置信度为47.74%）、四阶RMS（范围1的置信度为86.01%）和三叶草像差（C的置信度为56.38%，C的置信度为73.25%）的最小值点。在30至35岁年龄组中也观察到初级球差（C的置信度为56.10%）和垂直彗差样像差（C的置信度为56.91%）的最小值点。相比之下，顺规散光倾向于随年龄降低，而逆规散光和斜向散光倾向于增加（不同年龄组顺规散光的置信度分别为88.66%、84.71%、81.07%、79.67%和66.35%）。随着年龄增长，顺规散光人群减少，而逆规散光人群增加。高阶像差在25至35岁年龄组中最低。
