Wei Rui Hua, Lim Li, Chan Wing Kwong, Tan Donald T H
Tianjin Medical University Eye Centre, Tianjin, China.
J Refract Surg. 2006 Sep;22(7):695-702. doi: 10.3928/1081-597X-20060901-11.
To describe the characteristics of higher order ocular aberrations of adult Chinese eyes with myopia.
Higher order aberrations in consecutive right eyes of 166 Chinese patients with myopia who enrolled for preoperative assessment for LASIK were retrospectively reviewed. Wavefront aberrations were measured with the Bausch & Lomb Zywave over a 6-mm dilated pupil. The correlations between higher order aberrations and myopia, astigmatism, and age, respectively, were analyzed.
Mean patient age was 32.1 +/- 6.2 years, the mean refractive error was sphere -5.23 +/- 1.79 diopters (D) and cylinder -1.29 +/- 0.98 D. The mean of the total higher order root-mean-square (RMS) (third to fifth order) was 0.49 +/- 0.16 microm. Third-order RMS was largest (mean 0.37 +/- 0.16 microm), followed by fourth-order RMS (mean 0.29 +/- 0.11 microm). For individual higher order Zernike coefficients, spherical aberration (C4(0)) predominated with a mean of 0.23 +/- 0.14 microm. No correlation was found between total higher order RMS and myopia or between total higher order RMS and age. Small but statistically significant relationships were found in the following groups: age and vertical primary coma (C3(-1))(r=-0.206, P=.008); age and spherical aberration (C4(0)) (r=0.196, P=.012); and myopia and horizontal trefoil (C3(3)) (r=-0.158, P=.042).
Higher order aberrations varied among individuals with myopia. Third-order RMS was the predominant higher order aberration. Spherical aberration and vertical primary coma increased slightly with age. Our study helps establish ocular aberration standards for Chinese refractive surgery candidates.
描述成年中国近视患者的高阶眼像差特征。
回顾性分析166例因拟行准分子激光原位角膜磨镶术（LASIK）而进行术前评估的中国近视患者连续右眼的高阶像差。使用博士伦Zywave在6mm散瞳瞳孔下测量波前像差。分别分析高阶像差与近视、散光和年龄之间的相关性。
患者平均年龄为32.1±6.2岁，平均屈光不正为球镜-5.23±1.79屈光度（D），柱镜-1.29±0.98D。总高阶均方根（RMS）（三阶至五阶）平均值为0.49±0.16μm。三阶RMS最大（平均值0.37±0.16μm），其次是四阶RMS（平均值0.29±0.11μm）。对于单个高阶泽尼克系数，球差（C4(0)）占主导，平均值为0.23±0.14μm。未发现总高阶RMS与近视之间或总高阶RMS与年龄之间存在相关性。在以下几组中发现小但具有统计学意义的关系：年龄与垂直初级彗差（C3(-1)）（r=-0.206，P=0.008）；年龄与球差（C4(0)）（r=0.196, P=0.012）；近视与水平三叶形像差（C3(3)）（r=-0.158，P=0.042）。
近视患者个体间高阶像差各不相同。三阶RMS是主要的高阶像差。球差和垂直初级彗差随年龄略有增加。我们的研究有助于为中国屈光手术候选者建立眼像差标准。
