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用于FRS-洞穴M强子治疗的正电子发射体的生产与分离

Production and separation of positron emitters for hadron therapy at FRS-Cave M.

作者信息

Haettner E, Geissel H, Franczak B, Kostyleva D, Purushothaman S, Tanaka Y K, Amjad F, Boscolo D, Dickel T, Graeff C, Hessler C, Hornung C, Kazantseva E, Kuzminchuk N, Morrissey D, Mukha I, Pietri S, Rocco E, Roy P, Roesch H, Schuy C, Schütt P, Weber U, Weick H, Zhao J, Durante M, Parodi K, Scheidenberger C

机构信息

GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany.

II. Physikalisches Institut, Justus-Liebig-Universität, 35392, Gieβen, Germany.

出版信息

Nucl Instrum Methods Phys Res B. 2023 Aug;541:114-116. doi: 10.1016/j.nimb.2023.04.026. Epub 2023 May 19.

Abstract

The FRagment Separator FRS at GSI is a versatile spectrometer and separator for experiments with relativistic in-flight separated short-lived exotic beams. One branch of the FRS is connected to the target hall where the bio-medical cave (Cave M) is located. Recently a joint activity between the experimental groups of the FRS and the biophysics at the GSI and Department of physics at LMU was started to perform biomedical experiments relevant for hadron therapy with positron emitting carbon and oxygen beams. This paper presents the new ion-optical mode and commissioning results of the FRS-Cave M branch where positron emitting O-ions were provided to the medical cave for the first time. An overall conversion efficiency of 2.9±0.2×10 O fragments per primary O ion accelerated in the synchrotron SIS18 was reached.

摘要

位于德国重离子研究中心(GSI)的碎片分离器(FRS)是一种多功能光谱仪和分离器,用于相对论飞行中分离的短寿命奇异束流实验。FRS的一个分支连接到生物医学洞穴(洞穴M)所在的靶区大厅。最近,GSI的FRS实验组与生物物理学组以及慕尼黑大学(LMU)物理系开展了一项联合活动,以进行与正电子发射碳和氧束强子治疗相关的生物医学实验。本文介绍了FRS-洞穴M分支的新离子光学模式和调试结果,其中首次将正电子发射氧离子提供给医学洞穴。在同步加速器SIS18中加速的每个初级氧离子的总转换效率达到了2.9±0.2×10个氧碎片。

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引用本文的文献

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Sci Rep. 2023 Nov 1;13(1):18788. doi: 10.1038/s41598-023-45122-2.

本文引用的文献

1
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2
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3
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