Tran Mya, Palmer Shannon, Moore Dominic T, Bartelt Luther, Friedland Anne, Grgic Tatjana, Lachiewicz Anne, Ptachcinski Jon, Sena Arlene, Trepte Morgan, van Duin David, Andermann Tessa M, Shaw Ryan
Department of Pharmacy, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, USA.
Department of Pharmacy, Oregon Health and Sciences University, Portland, Oregon, USA.
Open Forum Infect Dis. 2023 May 3;10(5):ofad236. doi: 10.1093/ofid/ofad236. eCollection 2023 May.
The utility of obtaining screening urine cultures for febrile neutropenia (FN) during hematopoietic stem cell transplant (HCT) is unknown. In 667 adult HCT patients with FN, only 40 (6%) were found with bacteriuria. Antibiotics were modified in 3 patients (0.4%) based on urine cultures and none developed urinary-associated infectious complications.
在造血干细胞移植(HCT)期间,针对发热性中性粒细胞减少症(FN)进行筛查尿培养的实用性尚不清楚。在667例患有FN的成年HCT患者中,仅40例(6%)被发现有菌尿。基于尿培养结果,3例患者(0.4%)调整了抗生素治疗,且无一例发生与泌尿系统相关的感染并发症。