• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

造血干细胞移植受者在无泌尿系统症状的发热性中性粒细胞减少症检查中尿培养的效用。

Utility of Urine Cultures During Febrile Neutropenia Workup in Hematopoietic Stem Cell Transplantation Recipients Without Urinary Symptoms.

作者信息

Tran Mya, Palmer Shannon, Moore Dominic T, Bartelt Luther, Friedland Anne, Grgic Tatjana, Lachiewicz Anne, Ptachcinski Jon, Sena Arlene, Trepte Morgan, van Duin David, Andermann Tessa M, Shaw Ryan

机构信息

Department of Pharmacy, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, USA.

Department of Pharmacy, Oregon Health and Sciences University, Portland, Oregon, USA.

出版信息

Open Forum Infect Dis. 2023 May 3;10(5):ofad236. doi: 10.1093/ofid/ofad236. eCollection 2023 May.

DOI:10.1093/ofid/ofad236
PMID:37265665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10230562/
Abstract

The utility of obtaining screening urine cultures for febrile neutropenia (FN) during hematopoietic stem cell transplant (HCT) is unknown. In 667 adult HCT patients with FN, only 40 (6%) were found with bacteriuria. Antibiotics were modified in 3 patients (0.4%) based on urine cultures and none developed urinary-associated infectious complications.

摘要

在造血干细胞移植(HCT)期间,针对发热性中性粒细胞减少症(FN)进行筛查尿培养的实用性尚不清楚。在667例患有FN的成年HCT患者中,仅40例(6%)被发现有菌尿。基于尿培养结果,3例患者(0.4%)调整了抗生素治疗,且无一例发生与泌尿系统相关的感染并发症。

相似文献

1
Utility of Urine Cultures During Febrile Neutropenia Workup in Hematopoietic Stem Cell Transplantation Recipients Without Urinary Symptoms.造血干细胞移植受者在无泌尿系统症状的发热性中性粒细胞减少症检查中尿培养的效用。
Open Forum Infect Dis. 2023 May 3;10(5):ofad236. doi: 10.1093/ofid/ofad236. eCollection 2023 May.
2
Urine cultures at the onset of febrile neutropenia rarely impact antibiotic management in asymptomatic adult cancer patients.发热性中性粒细胞减少症发作时的尿液培养很少会影响无症状成年癌症患者的抗生素管理。
Support Care Cancer. 2019 Apr;27(4):1223-1227. doi: 10.1007/s00520-018-4476-7. Epub 2018 Sep 27.
3
Clinical features of febrile neutropenia and bloodstream infection in autologous hematopoietic cell transplantation: Comparison to those in intensive chemotherapy for acute myeloid leukemia.自体造血细胞移植中发热性中性粒细胞减少症和血流感染的临床特征:与急性髓系白血病强化化疗的临床特征比较。
J Infect Chemother. 2023 Apr;29(4):384-390. doi: 10.1016/j.jiac.2023.01.004. Epub 2023 Jan 18.
4
Risk Adapted Management of Febrile Neutrepenia and Early Cessation of Empirical Antibiotherapy in Hematopoietic Stem Cell Transplantation Setting.发热性中性粒细胞减少症的风险适应管理和造血干细胞移植环境中经验性抗生素治疗的早期停药。
Balkan Med J. 2017 Apr 5;34(2):132-139. doi: 10.4274/balkanmedj.2016.0012.
5
Antimicrobial de-escalation in adult hematopoietic cell transplantation recipients with febrile neutropenia of unknown origin.不明原因发热性中性粒细胞减少的成年造血细胞移植受者的抗菌药物降阶梯治疗
J Oncol Pharm Pract. 2020 Apr;26(3):632-640. doi: 10.1177/1078155219865303. Epub 2019 Aug 18.
6
Incidence of Febrile Neutropenia in Autologous Hematopoietic Stem Cell Transplant (HSCT) Recipients on levofloxacin prophylaxis.接受左氧氟沙星预防治疗的自体造血干细胞移植(HSCT)受者发热性中性粒细胞减少症的发生率。
Transpl Infect Dis. 2020 Apr;22(2):e13225. doi: 10.1111/tid.13225. Epub 2019 Dec 12.
7
Degree of mucositis and duration of neutropenia are the major risk factors for early post-transplant febrile neutropenia and severe bacterial infections after reduced-intensity conditioning.黏膜炎的严重程度和中性粒细胞减少的持续时间是导致低强度预处理后移植后早期发热性中性粒细胞减少和严重细菌感染的主要危险因素。
Eur J Haematol. 2012 Jan;88(1):46-51. doi: 10.1111/j.1600-0609.2011.01724.x.
8
Inpatient Antibiotic Stewardship Interventions in the Adult Oncology and Hematopoietic Stem Cell Transplant Population: A Review of the Literature.成人肿瘤和造血干细胞移植人群中的住院患者抗生素管理干预措施:文献综述。
Ann Pharmacother. 2020 Jun;54(6):594-610. doi: 10.1177/1060028019890886. Epub 2019 Nov 26.
9
Is urine culture necessary to rule out urinary tract infection in young febrile children?对于发热的幼儿,是否有必要进行尿培养以排除尿路感染?
Pediatr Infect Dis J. 1996 Apr;15(4):304-9. doi: 10.1097/00006454-199604000-00005.
10
Controversies in Treating Asymptomatic Bacteriuria and Urinary Tract Infection: A Case Based Review of Antibiotic Use in Renal Transplant Patients and its Impact on the Development of Resistance.无症状菌尿和尿路感染的治疗争议:基于病例的肾移植患者抗生素使用及其对耐药性发展影响的综述。
Indian J Pediatr. 2020 Jan;87(1):51-55. doi: 10.1007/s12098-019-03109-w. Epub 2019 Dec 11.

引用本文的文献

1
Urinary tract infections in immunocompromised patients.免疫功能低下患者的尿路感染
Curr Opin Infect Dis. 2025 Aug 1;38(4):322-328. doi: 10.1097/QCO.0000000000001121. Epub 2025 Jun 9.
2
Impact of urinary culture on diagnosis and treatment strategy after empiric therapy in febrile neutropenic patients.尿培养对发热性中性粒细胞减少症患者经验性治疗后诊断及治疗策略的影响。
Acute Med Surg. 2024 Nov 6;11(1):e70012. doi: 10.1002/ams2.70012. eCollection 2024 Jan-Dec.

本文引用的文献

1
Role of urine studies in asymptomatic febrile neutropenic patients presenting to the emergency department.尿液检查在急诊科就诊的无症状发热性中性粒细胞减少患者中的作用。
World J Emerg Med. 2021;12(2):99-104. doi: 10.5847/wjem.j.1920-8642.2021.02.003.
2
Urine cultures at the onset of febrile neutropenia rarely impact antibiotic management in asymptomatic adult cancer patients.发热性中性粒细胞减少症发作时的尿液培养很少会影响无症状成年癌症患者的抗生素管理。
Support Care Cancer. 2019 Apr;27(4):1223-1227. doi: 10.1007/s00520-018-4476-7. Epub 2018 Sep 27.
3
Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update.成人恶性肿瘤患者发热与中性粒细胞减少的门诊管理:美国临床肿瘤学会与感染病学会临床实践指南更新
J Clin Oncol. 2018 May 10;36(14):1443-1453. doi: 10.1200/JCO.2017.77.6211. Epub 2018 Feb 20.
4
The Diagnosis of UTI: Colony Count Criteria Revisited.尿路感染的诊断:重新审视菌落计数标准。
Pediatrics. 2018 Feb;141(2). doi: 10.1542/peds.2017-3239. Epub 2018 Jan 16.
5
Prevention and Treatment of Cancer-Related Infections, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology.《癌症相关感染的预防和治疗》,第 2.2016 版,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2016 Jul;14(7):882-913. doi: 10.6004/jnccn.2016.0093.
6
Low impact of urine cultures as a diagnostic tool in patients with neutropenic fever.尿培养作为中性粒细胞减少性发热患者诊断工具的作用有限。
Infect Dis (Lond). 2016 Nov-Dec;48(11-12):872-4. doi: 10.1080/23744235.2016.1205216. Epub 2016 Jul 8.
7
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america.抗菌药物在肿瘤中性粒细胞减少患者应用的临床实践指南:美国传染病学会 2010 年更新版。
Clin Infect Dis. 2011 Feb 15;52(4):e56-93. doi: 10.1093/cid/cir073.
8
Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults.美国传染病学会成人无症状菌尿症诊断和治疗指南。
Clin Infect Dis. 2005 Mar 1;40(5):643-54. doi: 10.1086/427507. Epub 2005 Feb 4.
9
Febrile neutropenia in allogeneic and autologous peripheral blood stem cell transplantation and conventional chemotherapy for malignancies.异基因和自体外周血干细胞移植及恶性肿瘤传统化疗中的发热性中性粒细胞减少症。
Bone Marrow Transplant. 2000 Jul;26(2):211-4. doi: 10.1038/sj.bmt.1702503.