Memorial Sloan Kettering Cancer Center.
University of California, San Francisco.
Clin J Oncol Nurs. 2023 May 18;27(3):259-265. doi: 10.1188/23.CJON.259-265.
Chronic graft-versus-host disease (cGVHD) is a significant complication for patients who receive allogeneic hematopoietic stem cell transplantation. This disease is further complicated for patients who are refractory to steroids. This article reviews emerging therapies and supportive care for patients with steroid-refractory cGVHD.
This article provides foundational knowledge on steroid-refractory cGVHD, emerging treatment options, and related supportive care.
Current research on emerging therapies for patients with steroid-refractory cGVHD is summarized along with supportive care recommendations and a review of related nursing considerations.
Emerging therapies for steroid-refractory cGVHD offer opportunities for improved clinical outcomes for these patients. Nursing knowledge of new therapies and supportive care for patients with steroid-refractory cGVHD supports the provision of optimal nursing care for a complex population of patients.
慢性移植物抗宿主病（cGVHD）是接受异基因造血干细胞移植患者的重大并发症。对于对类固醇耐药的患者，这种疾病会更加复杂。本文回顾了类固醇耐药性 cGVHD 患者的新兴疗法和支持性护理。
本文提供了关于类固醇耐药性 cGVHD 的基础知识、新兴治疗选择和相关支持性护理。
总结了类固醇耐药性 cGVHD 患者新兴疗法的当前研究，以及支持性护理建议和相关护理考虑因素的回顾。
类固醇耐药性 cGVHD 的新兴疗法为这些患者提供了改善临床结果的机会。护士对类固醇耐药性 cGVHD 患者新疗法和支持性护理的了解支持为复杂患者群体提供最佳护理。
