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犬胰管的显微外科重建

Microsurgical reconstruction of pancreatic ducts in dogs.

作者信息

Lamesch A J, Dociu N

出版信息

Surgery. 1986 Jul;100(1):121-5.

PMID:3726754
Abstract

The incidence of traumatic injuries of the pancreas has increased in patients sustaining abdominal trauma. The purpose of this study was to perfect the microsurgical technique of anastomosis of pancreatic ducts in dogs as a contribution to conservative treatment of the injured pancreas with salvage of the spleen to avoid sepsis after splenectomy. Eighteen mongrel dogs weighing an average 20 kg were used. The anastomoses were performed with an operating microscope with monofilament nylon 10-0 (Ethilon) and polyglactin 910 (Vicryl) 10-0 (0.2 m) swaged to a BV-6 taper-point needle. Retrograde pancreatography was performed before and after operation. Serum amylase determinations were made. Histologic and scanning electron microscopic examinations of the anastomoses were performed at different intervals after operation. Primary healing occurred in all cases. Reepithelialization of the suture line was completed between the twenty-eighth and forty-second postoperative days. Patency of the pancreatic ducts was revealed by pancreatography 4 months after surgery. In conclusion microsurgery offers an interesting perspective to reconstructive pancreatic surgery.

摘要

在遭受腹部创伤的患者中,胰腺创伤的发生率有所增加。本研究的目的是完善犬胰管吻合的显微外科技术,以促进对损伤胰腺的保守治疗,保留脾脏以避免脾切除术后发生败血症。使用了18只平均体重20公斤的杂种犬。使用手术显微镜,用10-0单丝尼龙线(Ethilon)和带BV-6锥形尖针的10-0(0.2米)聚乙醇酸910(Vicryl)进行吻合。术前和术后进行逆行胰管造影。测定血清淀粉酶。术后在不同时间间隔对吻合口进行组织学和扫描电子显微镜检查。所有病例均实现一期愈合。术后第28天至第42天之间,缝线处完成重新上皮化。术后4个月通过胰管造影显示胰管通畅。总之,显微外科为胰腺重建手术提供了一个有趣的前景。

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