Sawhney I M, Prabhakar S, Dhand U K, Chopra J S
Trans R Soc Trop Med Hyg. 1986;80(1):85-6. doi: 10.1016/0035-9203(86)90202-6.
Acute cerebellar ataxia as an isolated neurological manifestation of enteric fever is very rare. Three cases of acute cerebellar ataxia associated with enteric fever are reported. The diagnosis of enteric fever was confirmed by positive blood culture, strongly positive Widal test and rising antibody titres. The major clinical features were rapid development of gait ataxia, limb ataxia and dysarthria. None of the patients had altered sensorium. The cerebellar involvement was noticed on the second or third day of fever which progressed for one to two days. The symptoms remained static for one to two weeks and thereafter all the patients showed gradual recovery in a few weeks. Acute onset of cerebellar lesion, self limiting course and cerebrospinal fluid pleocytosis suggest par- or post-infectious demyelinating pathology in these patients, who were not related to each other.
急性小脑性共济失调作为伤寒的一种孤立性神经表现非常罕见。本文报告了3例与伤寒相关的急性小脑性共济失调病例。血培养阳性、肥达试验强阳性及抗体滴度升高确诊为伤寒。主要临床特征为步态共济失调、肢体共济失调和构音障碍迅速发展。所有患者均无意识改变。发热第2天或第3天出现小脑受累，并持续1至2天。症状持续1至2周，此后所有患者在数周内逐渐康复。小脑病变急性起病、自限病程及脑脊液淋巴细胞增多提示这些互不相关的患者存在感染性或感染后脱髓鞘病变。
