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70 岁老人莱姆神经根病。

Lyme radiculopathy in a septuagenarian.

机构信息

Orthopaedics, NHS Forth Valley, Larbert, UK.

Microbiology, NHS Forth Valley, Larbert, UK

出版信息

BMJ Case Rep. 2023 Jun 2;16(6):e251982. doi: 10.1136/bcr-2022-251982.

DOI:10.1136/bcr-2022-251982
PMID:37270176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10255208/
Abstract

A man in his 70s presented to hospital in early summer with a 5-week history of progressive lower back and right thigh pain, sensory deficit and right leg weakness. There had been limited response to analgesics in the community. Primary investigations on admission revealed no cause for his symptoms. Five days into admission, history emerged of a possible tick bite with subsequent rash sustained 3 months earlier, raising the possibility of neuroborreliosis leading to radiculopathy. Cerebrospinal fluid demonstrated a lymphocytic pleocytosis. An elevated antibody index confirmed a diagnosis of Lyme neuroborreliosis. The patient was treated successfully with 28 days of intravenous ceftriaxone, analgesia and physiotherapy. Within the literature, Lyme radiculopathy is a common presentation of neuroborreliosis and should be considered and investigated in patients without radiological evidence of a mechanical cause of worsening lower back pain in settings with endemic Lyme disease.

摘要

一位 70 多岁的男性初夏时因持续 5 周的下背部和右大腿疼痛、感觉缺失和右腿无力到医院就诊。在社区治疗中镇痛药的效果有限。入院时的初步检查未发现导致其症状的原因。住院 5 天后,出现了可能被蜱虫叮咬的病史,随后在 3 个月前出现皮疹,这增加了神经莱姆病导致神经根病的可能性。脑脊液显示淋巴细胞增多。升高的抗体指数证实了莱姆神经Borreliosis 的诊断。该患者接受了 28 天的静脉头孢曲松、镇痛和物理治疗,治疗成功。在文献中,莱姆神经根病是神经莱姆病的常见表现,在莱姆病流行地区,如果没有影像学证据表明下背部疼痛恶化是机械性原因引起的,应考虑并对这些患者进行检查。

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Lyme radiculopathy in a septuagenarian.70 岁老人莱姆神经根病。
BMJ Case Rep. 2023 Jun 2;16(6):e251982. doi: 10.1136/bcr-2022-251982.
2
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本文引用的文献

1
Primary HSV-2 Infection Complicated by Radiculomyelitis in a Young Immunocompetent Female Patient with Inherited Chromosomally Integrated HHV-6: A Case Report.原发性单纯疱疹病毒 2 型感染并发年轻免疫功能正常女性患者的脊神经根炎:病例报告。
Viruses. 2022 Sep 7;14(9):1979. doi: 10.3390/v14091979.
2
Prostate cancer screening using a combination of risk-prediction, MRI, and targeted prostate biopsies (STHLM3-MRI): a prospective, population-based, randomised, open-label, non-inferiority trial.使用风险预测、MRI 和靶向前列腺活检的组合进行前列腺癌筛查(STHLM3-MRI):一项前瞻性、基于人群、随机、开放标签、非劣效性试验。
Lancet Oncol. 2021 Sep;22(9):1240-1249. doi: 10.1016/S1470-2045(21)00348-X. Epub 2021 Aug 13.
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Cauda equina syndrome due to herpes simplex virus type 2-associated meningoradiculitis (Elsberg syndrome) after posterior lumbar spinal fusion surgery: Case report and review of literature.腰椎后路融合术后因2型单纯疱疹病毒相关性脑脊膜神经根炎(埃尔斯伯格综合征)导致的马尾综合征:病例报告及文献复习
Clin Neurol Neurosurg. 2021 Apr 1;205:106624. doi: 10.1016/j.clineuro.2021.106624.
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Serum C-reactive protein and WBC count in conservatively and operatively managed bacterial spondylodiscitis.保守治疗和手术治疗细菌性脊柱骨髓炎的血清 C 反应蛋白和白细胞计数。
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Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease.美国传染病学会(IDSA)、美国神经病学学会(AAN)和美国风湿病学会(ACR)临床实践指南:2020年莱姆病预防、诊断和治疗指南。
Arthritis Care Res (Hoboken). 2021 Jan;73(1):1-9. doi: 10.1002/acr.24495. Epub 2020 Nov 29.
6
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Open Forum Infect Dis. 2020 Aug 19;7(10):ofaa370. doi: 10.1093/ofid/ofaa370. eCollection 2020 Oct.
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COVID-19-associated Guillain-Barré syndrome: The early pandemic experience.COVID-19 相关的吉兰-巴雷综合征:早期大流行的经验。
Muscle Nerve. 2020 Oct;62(4):485-491. doi: 10.1002/mus.27024. Epub 2020 Aug 11.
8
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Korean J Pain. 2020 Jul 1;33(3):208-215. doi: 10.3344/kjp.2020.33.3.208.
9
Atypical presentation of Lyme neuroborreliosis related meningitis and radiculitis.莱姆病神经伯氏疏螺旋体病相关脑膜炎和神经根炎的非典型表现。
Neurol Int. 2019 Dec 2;11(4):8318. doi: 10.4081/ni.2019.8318. eCollection 2019 Nov 29.
10
A Review of Lumbar Radiculopathy, Diagnosis, and Treatment.腰椎神经根病的综述、诊断与治疗
Cureus. 2019 Oct 17;11(10):e5934. doi: 10.7759/cureus.5934.