Department of Urology and Reconstructive Andrology, Humanitas Gradenigo, Turin, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Urology Unit, Department of Surgery, S. Croce e Carle Hospital, Cuneo, Italy.
Eur Urol. 2023 Sep;84(3):313-320. doi: 10.1016/j.eururo.2023.05.019. Epub 2023 Jun 1.
Recent years have seen the development of a new generation of temporary urethral stents as an adjuvant option after direct vision internal urethrotomy (DVIU). Despite some early promising results, large series addressing their safety and outcomes are still lacking.
To report complications and outcomes from the largest series of patients receiving a temporary bulbar urethral stent to date.
DESIGN, SETTING, AND PARTICIPANTS: We performed a retrospective analysis of bulbar urethral stenting procedures after DVIU in seven centers. Patients either refused urethroplasty or were not fit for surgery. The stents were removed after at least 6 mo in place unless complications requiring earlier removal occurred.
DVIU with a cold knife or laser is performed, followed by stent placement. At the end of the treatment period, the stent is removed under cystoscopy with gripping forceps.
All patients underwent postoperative follow-up (FU) for assessment of complications while the stent was in place. After removal, the FU schedule consisted of office evaluation at 6 mo and 12 mo, and then annually. Failure was defined as any treatment for urethral stricture after stent removal.
A total of 49% of the patients experienced complications. The most frequent were discomfort (23.8%), stress incontinence (17.5%), and stent dislocation (9.8%). Some 85% of the adverse events observed were Clavien-Dindo grade <3. The overall success rate at median FU of 38.2 mo was 76.9%. The success rate was significantly lower if the stent was removed before 6 mo (53.3% vs 79.7%; p = 0.026).
Temporary urethral stents may be a safe choice with satisfactory results in patients not undergoing urethroplasty. A stent indwelling time shorter than 6 mo provides worse outcomes that are comparable to those with DVIU alone.
We assessed complications and outcomes after placement of a temporary narrow tube in the urethra after surgery to widen a narrowing of the urethra. The treatment is safe and easily reproducible with satisfactory results. Further studies are needed to confirm our findings.
近年来,作为直接视觉尿道内切开术(DVIU)后的辅助选择,出现了新一代的临时尿道支架。尽管早期有一些令人鼓舞的结果,但仍缺乏大规模的安全性和结果研究。
报告迄今为止接受临时球部尿道支架的最大系列患者的并发症和结果。
设计、地点和参与者:我们对 7 个中心的 DVIU 后球部尿道支架置入术进行了回顾性分析。患者拒绝接受尿道成形术或不适合手术。支架至少放置 6 个月后取出,除非出现需要提前取出的并发症。
行冷刀或激光 DVIU,然后置入支架。在治疗期结束时,在膀胱镜下用抓钳取出支架。
所有患者在支架置入期间接受术后随访(FU)以评估并发症。取出后,FU 计划包括 6 个月和 12 个月时的门诊评估,然后每年一次。支架取出后任何治疗尿道狭窄的方法均定义为失败。
共有 49%的患者出现并发症。最常见的是不适(23.8%)、压力性尿失禁(17.5%)和支架脱位(9.8%)。观察到的不良事件约 85%为 Clavien-Dindo 分级 <3。在中位数 FU 为 38.2 个月时,总体成功率为 76.9%。如果支架在 6 个月之前取出,成功率显著降低(53.3%比 79.7%;p=0.026)。
对于未行尿道成形术的患者,临时尿道支架可能是一种安全且结果满意的选择。支架留置时间短于 6 个月的患者预后较差,与单纯 DVIU 相当。
我们评估了手术后在狭窄的尿道中放置临时细管以扩大狭窄的并发症和结果。该治疗方法安全、易于复制,结果满意。需要进一步的研究来证实我们的发现。