From the Department of Anesthesiology and Reanimation, Aydin Adnan Menderes University School of Medicine, Aydin, Turkey.
From the Department of Biostatistics, Adnan Menderes University School of Medicine, Aydin, Turkey.
Ann Saudi Med. 2023 May-Jun;43(3):154-160. doi: 10.5144/0256-4947.2023.154. Epub 2023 Jun 1.
During the induction of general anesthesia, hemodynamic instability is a common occurrence in elderly hypertensive patients with increased arterial stiffness, which can cause undesirable complications. Pulse wave velocity (PWV) is an important indicator of arterial stiffness.
Investigate if preoperatively measured PWV is related to hemodynamic changes during induction of general anesthesia.
Prospective, case control.
University hospital.
The study was carried out between December 2018 and December 2019 in patients 50 years or older scheduled for elective otolaryngology with endotracheal intubation and who had an American Society of Anesthesiologists (ASA) score of I or II. Patients diagnosed with hypertension (HT) or receiving treatment for hypertension for systolic blood pressure (SBP) ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg were compared with non-hypertensive patients (non-HT) of matching age and gender.
PWV values between HT and non-HT patients and hypotension rates at the 30th second of induction, the 30th second of intubation, and the 90th second of intubation between the HT and non-HT groups.
139 (95 with HT and 44 non-HT) RESULTS: PWV was higher in the HT group than in the non-HT group (<.001). Hypotension at the 30th second of intubation in the HT group was significantly more frequent than in the non-HT group (=.025). PWV was higher in hypotensive (n=62) than in non-hypotensive patients but the difference was statistically significant only for PWV measured at 30th second of intubation (n=77) (=.018).
The easily and non-invasively measured preoperative PWV may be an effective means of predicting hypotension during the induction of general anesthesia at the 30th second of intubation in HT patients.
Numbers of patients in the groups were not the same, and the study was not sufficiently powered to investigate the effect of hypertensive medications on PWV and arterial stiffness.
None.
在全身麻醉诱导期间，动脉僵硬程度增加的老年高血压患者常出现血流动力学不稳定，这可能导致不良并发症。脉搏波速度（PWV）是动脉僵硬的一个重要指标。
研究术前测量的 PWV 是否与全身麻醉诱导期间的血流动力学变化有关。
前瞻性病例对照研究。
大学医院。
该研究于 2018 年 12 月至 2019 年 12 月在择期行气管内插管耳鼻喉科手术的 50 岁及以上患者中进行，这些患者的美国麻醉医师协会（ASA）评分为 I 或 II 级。将诊断为高血压（HT）或因收缩压（SBP）≥140mmHg 和/或舒张压≥90mmHg 而接受降压治疗的患者与年龄和性别相匹配的非高血压患者（非-HT）进行比较。
HT 患者与非-HT 患者之间的 PWV 值以及 HT 组和非-HT 组诱导后 30 秒、插管后 30 秒和插管后 90 秒的低血压发生率。
139 例（95 例 HT 和 44 例非-HT）。
HT 组的 PWV 高于非-HT 组（<.001）。HT 组插管后 30 秒时低血压的发生率明显高于非-HT 组（=.025）。低血压患者（n=62）的 PWV 高于非低血压患者，但仅在插管后 30 秒测量的 PWV 上差异有统计学意义（n=77）（=.018）。
术前易测量且非侵入性的 PWV 可能是预测 HT 患者全身麻醉诱导后 30 秒插管时低血压的有效手段。
组间患者数量不相同，且研究未充分放大以调查降压药物对 PWV 和动脉僵硬的影响。
无。
