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治疗精神分裂症阴性症状：当前方法和未来展望。

Treating negative symptoms of schizophrenia: current approaches and future perspectives.

机构信息

Department of Psychosis Studies, King's College London, UK.

Department of Brain and Behavioral Health Sciences, University of Pavia, Italy.

出版信息

Br J Psychiatry. 2023 Jul;223(1):332-335. doi: 10.1192/bjp.2023.57.

DOI:10.1192/bjp.2023.57
PMID:37272623
Abstract

Negative symptoms are core symptoms of schizophrenia which are common throughout the course of the illness. We outline their functional impact, before reviewing the latest research and guidelines on their assessment and treatment. Finally, we discuss conceptual issues related to measurement of negative symptoms and approaches to address these.

摘要

阴性症状是精神分裂症的核心症状，在疾病过程中普遍存在。我们首先概述了它们的功能影响，然后回顾了关于其评估和治疗的最新研究和指南。最后，我们讨论了与阴性症状测量相关的概念问题以及解决这些问题的方法。

相似文献

[1]
Treating negative symptoms of schizophrenia: current approaches and future perspectives.

Br J Psychiatry. 2023-7

[2]
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[3]
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Lancet Psychiatry. 2020-9

[4]
Impact of atypical antipsychotics on quality of life in patients with schizophrenia.

CNS Drugs. 2004

[5]
The role of negative symptoms and cognitive dysfunction in schizophrenia outcome.

Int Clin Psychopharmacol. 1998-3

[6]
[Negative symptoms in schizophrenia: psychotherapeutic approaches].

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[7]
Covariation between motor signs and negative symptoms in drug-naive subjects with schizophrenia-spectrum disorders before and after antipsychotic treatment.

Schizophr Res. 2017-8-30

[8]
[Influences of second generation antipsychotics on the course of schizophrenia].

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[9]
[The quest for the pharmacological treatment of schizophrenia: from conventional neuroleptics to atypical antipsychotics and beyond].

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[10]
[Negative symptoms: which antipsychotics?].

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[1]
Efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with treatment-resistant schizophrenia with predominantly negative symptoms: a randomized clinical trial and efficacy sensitivity biomarkers.

Mol Psychiatry. 2025-8-26

[2]
Effects of antipsychotics on human cognitive function: causal evidence from healthy volunteers following sustained D2/D3 antagonism, D2/D3 partial agonism and placebo.

Mol Psychiatry. 2025-7-19

[3]
Mindfulness improves negative psychotic symptoms through reducing emotional and social withdrawal.

World J Psychiatry. 2025-4-19

[4]
Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour.

Nat Commun. 2025-2-21

[5]
Negative Symptoms in Schizophrenia: An Update on Research Assessment and the Current and Upcoming Treatment Landscape.

CNS Drugs. 2025-3

[6]
The efficacy and safety of dual-target rTMS over dorsolateral prefrontal cortex (DLPFC) and cerebellum in the treatment of negative symptoms in first-episode schizophrenia: Protocol for a multicenter, randomized, double-blind, sham-controlled study.

Schizophr Res Cogn. 2024-11-29

[7]
Pharmacological Treatments of Negative Symptoms in Schizophrenia-An Update.

J Clin Med. 2024-9-23

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