Technau-Hafsi Kristin, Garzorz-Stark Natalie, Eyerich Kilian
Klinik für Dermatologie und Venerologie, Medizinische Fakultät, Universität Freiburg, Freiburg, Deutschland.
Universitäts-Hautklinik Freiburg, Hauptstr. 7, 79104, Freiburg, Deutschland.
Dermatologie (Heidelb). 2023 Jun;74(6):410-415. doi: 10.1007/s00105-023-05148-z. Epub 2023 Jun 5.
Because hand eczema is a diagnostic challenge even for experienced dermatologists, a correct diagnosis is essential to ensure success of specific therapies.
Prerequisites for successful molecular diagnostics in general and in hand eczema in particular are discussed.
Basic research and opinion statement on new developments in molecular diagnostics are considered with a special focus on hand eczema.
The first molecular classifier to distinguish psoriasis from (hand) eczema signature has been introduced as CE-marked in vitro diagnostics (CE-IVD); many more biomarkers associated with diagnostics, theranostics, or natural course of the disease are currently being investigated.
Diagnosis of hand eczema will be supported by molecular diagnostics in the near future; we are at the beginning of the molecular era in dermatology.
手部湿疹即使对于经验丰富的皮肤科医生来说也是一项诊断挑战，正确诊断对于确保特定治疗的成功至关重要。
讨论一般情况下尤其是手部湿疹成功进行分子诊断的先决条件。
考虑了关于分子诊断新进展的基础研究和观点陈述，特别关注手部湿疹。
首个用于区分银屑病与（手部）湿疹特征的分子分类器已作为CE标志的体外诊断试剂（CE-IVD）推出；目前正在研究更多与疾病诊断、治疗诊断或自然病程相关的生物标志物。
在不久的将来，分子诊断将有助于手部湿疹的诊断；我们正处于皮肤科分子时代的开端。
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