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EASI p-EASI: Predicting disease severity in atopic dermatitis patients treated with dupilumab using a combination of serum biomarkers.

作者信息

Bakker Daphne S, Ariens Lieneke F M, Giovannone Barbara, Hijnen DirkJan, Delemarre Eveline M, Knol Edward, Nierkens Stefan, de Bruin-Weller Marjolein S, Thijs Judith L, Drylewicz Julia

机构信息

Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.

Center for Translational Immunology, Utrecht, The Netherlands.

出版信息

Allergy. 2020 Dec;75(12):3287-3289. doi: 10.1111/all.14492. Epub 2020 Jul 24.

DOI:10.1111/all.14492
PMID:33305359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7754122/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d178/7754122/759268b91616/ALL-75-3287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d178/7754122/46950635981f/ALL-75-3287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d178/7754122/759268b91616/ALL-75-3287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d178/7754122/46950635981f/ALL-75-3287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d178/7754122/759268b91616/ALL-75-3287-g002.jpg

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本文引用的文献

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Dupilumab is very effective in a large cohort of difficult-to-treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry.度普利尤单抗在一大群难治性成人特应性皮炎患者中非常有效:来自 BioDay 登记处的首个临床和生物标志物结果。
Allergy. 2020 Jan;75(1):116-126. doi: 10.1111/all.14080. Epub 2019 Oct 31.
2
EASI p-EASI: Predicting disease severity in atopic dermatitis patients treated with cyclosporin A.湿疹面积及严重程度指数(EASI)与改良湿疹面积及严重程度指数(p-EASI):预测接受环孢素A治疗的特应性皮炎患者的疾病严重程度
Allergy. 2019 Mar;74(3):613-617. doi: 10.1111/all.13651. Epub 2018 Dec 16.
3
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis.
Exploring the Potential of IL-4 and IL-13 Plasma Levels as Biomarkers in Atopic Dermatitis.
探索白细胞介素-4和白细胞介素-13血浆水平作为特应性皮炎生物标志物的潜力。
Life (Basel). 2024 Mar 7;14(3):352. doi: 10.3390/life14030352.
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Prediction of disease severity using serum biomarkers in patients with mild-moderate Atopic Dermatitis: A pilot study.使用血清生物标志物预测轻度至中度特应性皮炎患者的疾病严重程度:一项初步研究。
PLoS One. 2023 Nov 2;18(11):e0293332. doi: 10.1371/journal.pone.0293332. eCollection 2023.
5
[Molecular diagnosis of hand eczema].[手部湿疹的分子诊断]
Dermatologie (Heidelb). 2023 Jun;74(6):410-415. doi: 10.1007/s00105-023-05148-z. Epub 2023 Jun 5.
6
Dupilumab in daily practice for the treatment of pediatric atopic dermatitis: 28-week clinical and biomarker results from the BioDay registry.度普利尤单抗在特应性皮炎患儿中的临床应用:BioDay 注册研究 28 周的临床和生物标志物结果。
Pediatr Allergy Immunol. 2022 Dec;33(12):e13887. doi: 10.1111/pai.13887.
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J Allergy Clin Immunol. 2019 Jan;143(1):155-172. doi: 10.1016/j.jaci.2018.08.022. Epub 2018 Sep 5.
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Therapeutic pipeline for atopic dermatitis: End of the drought?特应性皮炎的治疗领域:干旱的尽头?
J Allergy Clin Immunol. 2017 Sep;140(3):633-643. doi: 10.1016/j.jaci.2017.07.006.
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EASI p-EASI: Utilizing a combination of serum biomarkers offers an objective measurement tool for disease severity in atopic dermatitis patients.湿疹面积及严重程度指数(EASI)与改良湿疹面积及严重程度指数(p-EASI):联合使用多种血清生物标志物可为特应性皮炎患者的疾病严重程度提供一种客观的测量工具。
J Allergy Clin Immunol. 2017 Dec;140(6):1703-1705. doi: 10.1016/j.jaci.2017.06.046. Epub 2017 Aug 16.
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Biomarkers for atopic dermatitis: a systematic review and meta-analysis.特应性皮炎的生物标志物:一项系统评价和荟萃分析。
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Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.辅助性T细胞17细胞因子白细胞介素(IL)-17和IL-22调节不同的炎症和角质形成细胞反应途径。
Br J Dermatol. 2008 Nov;159(5):1092-102. doi: 10.1111/j.1365-2133.2008.08769.x. Epub 2008 Aug 5.
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J Dermatol Sci. 1994 Apr;7(2):89-95. doi: 10.1016/0923-1811(94)90081-7.