Garzorz-Stark Natalie, Eyerich Kilian
Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, TU München, Biedersteiner Str. 29, 80802, München, Deutschland.
Hautarzt. 2019 Oct;70(10):760-765. doi: 10.1007/s00105-019-4466-9.
Using current diagnostic tools for hand eczema, namely clinical picture and histology, differential diagnoses such as psoriasis palmaris usually cannot be ruled out.
Discussion of current diagnostic possibilities for hand eczema; presentation and critical evaluation of proposed biomarkers for molecular diagnostics and outlook how diagnostics in dermatology will change in the near future.
In this article, we discuss basic research and provide a review of the literature.
Molecular diagnostics has the potential to substantially improve diagnosis of hand eczema; prerequisites are prospective validation of proposed markers and availability of valid and cost-effective diagnostics.
In the near future, the diagnosis of hand eczema will be complemented by software algorithms and artificial intelligence on the one hand and simple, precise, and economic molecular diagnostic devices on the other.
使用当前用于手部湿疹的诊断工具，即临床表现和组织学检查，通常无法排除诸如掌部银屑病等鉴别诊断。
讨论手部湿疹当前的诊断可能性；介绍并批判性评估用于分子诊断的拟议生物标志物，并展望皮肤病学诊断在不久的将来将如何变化。
在本文中，我们讨论基础研究并提供文献综述。
分子诊断有潜力大幅改善手部湿疹的诊断；前提是拟议标志物的前瞻性验证以及有效且经济高效的诊断方法的可用性。
在不久的将来，手部湿疹的诊断一方面将由软件算法和人工智能进行补充，另一方面将由简单、精确且经济的分子诊断设备进行补充。
