Oujdad Soukaïna, Ben Yahya Ihsane
Department of Oral Medicine and Oral Surgery, Faculty of Dental Medicine of Casablanca, Casablanca, MAR.
Cureus. 2023 May 2;15(5):e38432. doi: 10.7759/cureus.38432. eCollection 2023 May.
Oral lichen planus (OLP) is a chronic auto-immune disease associated with cell-mediated immunologic dysfunction whose etiology remains unknown. Malignant transformation into squamous cell carcinoma (SCC) is the most feared complication of OLP. It is actually recognized as a potentially malignant disorder with an unspecified risk of transformation, and it is suggested to closely monitor diagnosed patients. In this paper, we discuss the case of a 62-year-old female patient, a non-smoker, and non-drinker, who initially presented with painful erosive lesions on the edentulous mandibular ridge, the buccal mucosa, and the floor of the mouth. Clinical and histological findings led to the diagnosis of OLP with no signs of oral epithelial dysplasia. Malignant transformation into SCC was reported eight months after the first presentation.
口腔扁平苔藓（OLP）是一种与细胞介导的免疫功能障碍相关的慢性自身免疫性疾病，其病因尚不清楚。恶变为鳞状细胞癌（SCC）是OLP最可怕的并发症。它实际上被认为是一种具有未明确恶变风险的潜在恶性疾病，建议对确诊患者进行密切监测。在本文中，我们讨论了一例62岁女性患者的病例，该患者不吸烟、不饮酒，最初表现为无牙下颌牙槽嵴、颊黏膜和口底出现疼痛性糜烂性病变。临床和组织学检查结果诊断为OLP，无口腔上皮发育异常迹象。首次就诊8个月后报告发生了恶变为SCC。
