Montero Pablo H, Patel Snehal G
Head and Neck Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Head and Neck Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Surg Oncol Clin N Am. 2015 Jul;24(3):491-508. doi: 10.1016/j.soc.2015.03.006. Epub 2015 Apr 15.
Cancer of the oral cavity is one of the most common malignancies worldwide. Although early diagnosis is relatively easy, presentation with advanced disease is not uncommon. The standard of care is primary surgical resection with or without postoperative adjuvant therapy. Improvements in surgical techniques combined with the routine use of postoperative radiation or chemoradiation therapy have resulted in improved survival. Successful treatment is predicated on multidisciplinary treatment strategies to maximize oncologic control and minimize impact of therapy on form and function. Prevention of oral cancer requires better education about lifestyle-related risk factors, and improved awareness and tools for early diagnosis.
口腔癌是全球最常见的恶性肿瘤之一。虽然早期诊断相对容易,但出现晚期疾病的情况也并不罕见。治疗的标准是进行一期手术切除,可辅以或不辅以术后辅助治疗。手术技术的改进以及术后放疗或放化疗的常规使用已使生存率得到提高。成功的治疗取决于多学科治疗策略,以最大限度地实现肿瘤控制,并将治疗对形态和功能的影响降至最低。预防口腔癌需要更好地开展与生活方式相关风险因素的教育,并提高早期诊断的意识和手段。