用单克隆抗体对猫视网膜神经节细胞进行特异性标记。

Specific labelling of ganglion cells in the cat retina by a monoclonal antibody.

作者信息

Fry K R, Lam D M

出版信息

Vision Res. 1986;26(3):373-82. doi: 10.1016/0042-6989(86)90180-x.

Abstract

The introduction of monoclonal antibody technology has made it possible to produce specific markers for various retinal cell types. We report here on a monoclonal antibody, AB5, which specifically labels the retinal ganglion cells of the cat. The labelled cells could be categorized as either alpha, beta or gamma subtype based on morphological criteria. This antibody will be useful for studies of the morphology, localization and synaptic connectivity of ganglion cells in the cat retina.

摘要

单克隆抗体技术的引入使得为各种视网膜细胞类型产生特异性标记物成为可能。我们在此报告一种单克隆抗体AB5，它能特异性标记猫的视网膜神经节细胞。根据形态学标准，标记的细胞可分为α、β或γ亚型。这种抗体将有助于对猫视网膜神经节细胞的形态、定位和突触连接进行研究。