一种对哺乳动物视网膜神经节细胞具有特异性的单克隆抗体。

A monoclonal antibody specific for retinal ganglion cells of mammals.

作者信息

Fry K R, Tavella D, Su Y Y, Peng Y W, Watt C B, Lam D M

出版信息

Brain Res. 1985 Jul 15;338(2):360-5. doi: 10.1016/0006-8993(85)90169-6.

Abstract

The development of specific markers for retinal ganglion cells is an area of great interest in retinal research. In this study we report on a monoclonal antibody (AB5) which specifically labels ganglion cells in rabbit, cat and monkey, as well as a variety of other mammalian species. Labelling of ganglion cells was also observed in isolated cell preparations of rabbit retina.

摘要

视网膜神经节细胞特异性标志物的开发是视网膜研究中一个备受关注的领域。在本研究中，我们报告了一种单克隆抗体（AB5），它能特异性标记兔、猫和猴以及多种其他哺乳动物物种的神经节细胞。在兔视网膜的分离细胞制剂中也观察到了神经节细胞的标记。