病例报告：具有软骨黏液样基质的胃癌，类似产生基质的化生型乳腺癌：一种未描述实体的报告。

Case Report: Gastric cancer with chondromyxoid matrix similar matrix-producing metaplastic breast carcinoma: report of an undescribed entity.

作者信息

Wu Xiaoyan, He Huihua, Zhao Lina, Zeng Zhi, Yuan Jingping

机构信息

Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, China.

Department of Pathology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Front Oncol. 2023 May 19;13:1087241. doi: 10.3389/fonc.2023.1087241. eCollection 2023.

DOI:10.3389/fonc.2023.1087241

PMID:37274268

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10235811/

Abstract

Gastric cancer is a malignant epithelial neoplasm of the stomach, including adenocarcinoma, squamous cell carcinoma, adenosquamous carcinoma, undifferentiated carcinoma, gastroblastoma and neuroendocrine neoplasms, without gastric metaplastic carcinoma. We describe a 69-year-old male patient with gastric cancer who presented with a novel, biphasic histologic morphology with one component consisting of poorly differentiated adenocarcinoma and the other component consisting of chondromyxoid matrix with adenocarcinoma transition to, between the two components without a spindle cell component. The histological morphology of this case is similar to matrix-producing metaplastic breast carcinoma. Therefore, we diagnose this case as gastric carcinoma with chondromyxoid matrix similar matrix-producing metaplastic breast carcinoma.

摘要

胃癌是胃的一种恶性上皮性肿瘤，包括腺癌、鳞状细胞癌、腺鳞癌、未分化癌、胃母细胞瘤和神经内分泌肿瘤，不包括胃化生癌。我们描述了一名69岁的胃癌男性患者，其呈现出一种新的双相组织形态，一个成分由低分化腺癌组成，另一个成分由软骨黏液样基质组成，腺癌在这两个成分之间过渡，且无梭形细胞成分。该病例的组织形态与产生基质的化生型乳腺癌相似。因此，我们将该病例诊断为具有软骨黏液样基质的胃癌，类似于产生基质的化生型乳腺癌。