Carey Megan E, Dyson Zoe A, Argimón Silvia, Cerdeira Louise, Yeats Corin, Aanensen David, Mboowa Gerald, Baker Stephen, Tessema Sofonias K, Smith Anthony M, Okeke Iruka N, Holt Kathryn E
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
IAVI, Chelsea & Westminster Hospital, London, United Kingdom.
Open Forum Infect Dis. 2023 Jun 2;10(Suppl 1):S38-S46. doi: 10.1093/ofid/ofad044. eCollection 2023 May.
The global response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic demonstrated the value of timely and open sharing of genomic data with standardized metadata to facilitate monitoring of the emergence and spread of new variants. Here, we make the case for the value of Typhi (. Typhi) genomic data and demonstrate the utility of freely available platforms and services that support the generation, analysis, and visualization of Typhi genomic data on the African continent and more broadly by introducing the Africa Centres for Disease Control and Prevention's Pathogen Genomics Initiative, SEQAFRICA, Typhi Pathogenwatch, TyphiNET, and the Global Typhoid Genomics Consortium.
全球对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行的应对表明，及时、开放地共享带有标准化元数据的基因组数据对于促进监测新变种的出现和传播具有重要价值。在此，我们阐述了伤寒杆菌（. Typhi）基因组数据的价值，并通过介绍非洲疾病控制和预防中心的病原体基因组计划、SEQAFRICA、伤寒杆菌病原体监测、伤寒杆菌网络以及全球伤寒基因组学联盟，展示了免费可用平台和服务在支持非洲大陆及更广泛地区伤寒杆菌基因组数据的生成、分析和可视化方面的效用。
