Starosel'skiĭ I V
Vopr Onkol. 1986;32(6):66-71.
Early postoperative changes in cardiac hemodynamics were studied in 222 patients with cancer of the lung, esophagus, stomach and rectum. They took form of operative stress--associated sympathoadrenal stimulation of the heart, such as tachycardia, shorter period of isometric contraction, increased dP/dt and hyperdynamic syndrome. In cases of radical surgery, the said disorders were accompanied by decreased circulating blood and stroke volumes and, in most patients, by lowered cardiac output and blood pressure matched by enhanced peripheral vascular resistance. The said disturbances were more pronounced and persisted longer in cases of combined treatment, patients aged over 60 years and those with preexisting heart pathology. A correlation was established between the extent of these disorders, on the one hand, and blood loss and sympathoadrenal system response to operative stress, on the other.
对222例肺癌、食管癌、胃癌和直肠癌患者术后早期心脏血流动力学变化进行了研究。这些变化表现为手术应激相关的心脏交感肾上腺刺激,如心动过速、等长收缩期缩短、dP/dt增加和高动力综合征。在根治性手术病例中,上述紊乱伴有循环血量和每搏量减少,且大多数患者心输出量降低、血压下降,同时外周血管阻力增加。在联合治疗病例、60岁以上患者以及已有心脏病变的患者中,上述紊乱更为明显且持续时间更长。一方面,这些紊乱的程度与失血量和交感肾上腺系统对手术应激的反应之间建立了相关性。