一名泰国女性因肺炎克雷伯菌感染导致急性暴发性紫癜：病例报告及文献综述
Klebsiella-induced acute infectious purpura fulminans in a Thai woman: Case report and review of literature.
作者信息
Temnithikul Bhakinai, Rungrunanghiranya Suthat, Limtanyakul Piyakan, Angkananard Teeranan, Wessagowit Vesarat
机构信息
Department of Medicine HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University Ongkharak Nakhon Nayok Thailand.
HRH Princess Chulabhorn College of Medical Science Bangkok Thailand.
出版信息
Skin Health Dis. 2022 Nov 6;3(3):e186. doi: 10.1002/ski2.186. eCollection 2023 Jun.
Purpura fulminans (PF) is an uncommon syndrome of acute purplish skin eruption characterized by coagulation of the microvasculature, which leads to purplish lesions and skin necrosis. There are three subtypes; idiopathic PF, neonatal PF and, the most common subtype, acute infectious PF (AIPF). Acute infectious PF is related to the thrombotic subtype of disseminated intravascular coagulation (DIC) and usually is superimposed on sepsis. This can rapidly lead to multi-organ failure from thrombotic occlusion of small and medium-sized blood vessels. We report a case of Klebsiella-induced AIPF in a 78-year-old Thai woman and also review other published cases.
暴发性紫癜（PF）是一种罕见的急性紫色皮疹综合征，其特征为微血管内凝血，可导致紫色病变和皮肤坏死。它有三种亚型：特发性PF、新生儿PF以及最常见的亚型——急性感染性PF（AIPF）。急性感染性PF与弥散性血管内凝血（DIC）的血栓形成亚型有关，通常叠加于败血症之上。这可迅速导致中小血管血栓性闭塞引起多器官功能衰竭。我们报告一例78岁泰国女性由肺炎克雷伯菌引起的AIPF病例，并对其他已发表病例进行综述。
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