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节律性听觉刺激作为帕金森病潜在的神经调节剂。

Rhythmic auditory stimulation as a potential neuromodulator for Parkinson's disease.

机构信息

Music and Health Science Research Collaboratory, Faculty of Music, University of Toronto, 90 Wellesley Street West, Toronto, ON, M5S 1C5, Canada.

出版信息

Parkinsonism Relat Disord. 2023 Aug;113:105459. doi: 10.1016/j.parkreldis.2023.105459. Epub 2023 Jun 1.

DOI:10.1016/j.parkreldis.2023.105459
PMID:37277293
Abstract

Auditory rhythm-based therapeutic interventions such as rhythmic auditory stimulation (RAS) are effective in improving gait and balance and preventing falls in idiopathic Parkinson's disease (PD). Research showing associated neuromodulatory effects of RAS on brain oscillations is also emerging. The neuromodulation may be induced by neural entrainment and cross-frequency oscillatory coupling. Auditory rhythm and RAS based interventions are potentially effective in improving other PD symptoms and can be extended to atypical parkinsonism.

摘要

基于听觉节律的治疗干预,如节律性听觉刺激(RAS),在改善特发性帕金森病(PD)患者的步态和平衡以及预防跌倒方面是有效的。研究也表明,RAS 对脑电波产生了相关的神经调节作用。这种神经调节可能是由神经同步和跨频振荡耦合引起的。基于听觉节律和 RAS 的干预措施可能在改善其他 PD 症状方面也具有潜在的有效性,并且可以扩展到非典型帕金森病。

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