Obstetrics department, Shenzhen Longhua District Central Hospital, Shenzhen, China.
Obstetrics department, The First Dongguan Affiliated Hospital of Guangdong Medical University, Dongguan, China.
BMC Pregnancy Childbirth. 2023 Jun 5;23(1):417. doi: 10.1186/s12884-023-05734-y.
The aim of this study was to estimate predictors for vaginal birth following balloon catheter induction of labor (IOL) in women with one previous cesarean section (CS) and an unfavorable cervix.
This 4-year retrospective cohort study was conducted in Longhua District Central Hospital in Shenzhen China, between January 2015 and December 2018. Patients with one previous CS and a current singleton-term pregnancy who underwent balloon catheter cervical ripening and IOL were enrolled. Univariate analysis was used to identify predictive factors associated with vaginal birth after cesarean section (VBAC). Binary logistic regression was further used to identify which factors were independently associated with the outcome measure. The primary outcome was VBAC, which was a successful trial of labor after cesarean delivery (TOLAC) following IOL.
A total of 69.57% (208/299) of the women who planned for IOL had VBAC. In the final binary logistic regression equation, lower fetal weight (< 4000 g) (odds ratio [OR]5.26; 95% confidence interval [CI] 2.09,13.27), lower body mass index (BMI,<30 kg/m) (OR 2.27; CI 1.21, 4.26), Bishop score after cervical ripening > 6 (OR 1.94; CI 1.37, 2.76) remained independently associated with an increased chance of VBAC.
The influencing factors of VBAC following IOL were fetal weight, BMI, and Bishop score after cervical ripening. Adequate individualized management and assessment of the IOL may help improve the VBAC rate.
本研究旨在评估既往有 1 次剖宫产史且宫颈条件不佳的产妇行球囊导管引产(IOL)后阴道分娩的预测因素。
这是一项在中国深圳龙华区中心医院进行的 4 年回顾性队列研究,时间为 2015 年 1 月至 2018 年 12 月。纳入接受球囊导管宫颈成熟和 IOL 且既往有 1 次剖宫产史和目前单胎足月妊娠的患者。采用单因素分析确定与剖宫产术后阴道分娩(VBAC)相关的预测因素。进一步采用二元逻辑回归分析确定与结局指标独立相关的因素。主要结局是 IOL 后成功的剖宫产试产(TOLAC),即 VBAC。
计划行 IOL 的患者中,69.57%(208/299)有 VBAC。在最终的二元逻辑回归方程中,较低的胎儿体重(<4000 g)(优势比 [OR]5.26;95%置信区间 [CI]2.09,13.27)、较低的体重指数(BMI,<30 kg/m)(OR 2.27;CI 1.21,4.26)、宫颈成熟后 Bishop 评分>6(OR 1.94;CI 1.37,2.76)与 VBAC 机会增加独立相关。
IOL 后 VBAC 的影响因素为胎儿体重、BMI 和宫颈成熟后 Bishop 评分。充分的个体化管理和 IOL 评估可能有助于提高 VBAC 率。