Department of Neurology, Laboratory for Neurotherapeutics, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, 03080, South Korea; Department of Neurology, Dong-A University Hospital, Busan, 49315, South Korea.
Department of Neurology, Laboratory for Neurotherapeutics, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
J Infect Chemother. 2023 Oct;29(10):985-987. doi: 10.1016/j.jiac.2023.05.021. Epub 2023 Jun 4.
Ventriculitis has serious complications and a high mortality rate, so it is important to early identification of the pathogen for appropriate treatment. We report case of ventriculitis caused by Talaromyces rugulosus, a rare pathogen, in South Korea. Affected patient was immunocompromised. Repeated cerebrospinal fluid culture tests were negative, but the pathogen was identified by fungal internal transcribed spacer amplicon nanopore sequencing. The pathogen was detected outside the endemic area of talaromycosis.
心内膜炎有严重的并发症和高死亡率，因此早期确定病原体并进行适当的治疗非常重要。我们报告了一例由棘孢木霉引起的心内膜炎，棘孢木霉是一种罕见的病原体，在韩国。受影响的患者免疫功能低下。反复的脑脊液培养试验为阴性，但通过真菌内部转录间隔区扩增子纳米孔测序鉴定出病原体。该病原体在棘孢霉病的流行地区之外被检测到。
