ACCUMULATION OF 4-O-β-D-GLUCOSIDE OF PROTOCATECHUIC ACID IN THE LEFT COLLETERIAL GLAND OF THE COCKROACH, PERIPLANETA AMERICANA. II. HORMONAL REGULATION.

The amount of protocatechuic acid glucoside in the left colleterial gland changes with the reproductive cycle. Allatectomy, beheading and injection of actinomycin D cause inhibition of the accumulation of glucoside, but glucoside resumes to accumulate in the left colleterial gland with the reimplantation of corpora allata into the allatectomized cockroaches. When C-glucose was injected in normal animals, radioactive glucoside was accumulated in the left colleterial gland whereas in the allatectomized cockroaches, it was not accumulated in the gland but was found abundantly in blood. The level of protocatechuic acid glucoside synthetase activity of the fat body tissue and of the left colleterial gland was assayed. The enzyme activity in the left colleterial gland was not affected by allatectomy but that in the fat body was slightly affected. The mechanism of accumulation of protocatechuic acid glucoside in the left colleterial gland and the endocrine control on the accumulation are discussed.